Martínez Campanario, María del Carmen (Date of defense: 2021-05-27)
Macrophages polarization from an inflammatory to a tolerogenic state occurs in both physiological and pathological, and this reprogramming is key in the development of several diseases as different as ...
Rodríguez-Vida Rodríguez, Alejo (Date of defense: 2017-10-23)
Prostate cancer is the second most frequently diagnosed cancer worldwide and the fifth leading cause of cancer death in men. Despite, the above mentioned incidence and mortality, the existence of a small ...
Roura Fornells, Esther (Date of defense: 2018-10-22)
The objective of this thesis is to estimate prospectively the association between environmental cofactors and the risk of developing cervical cancer and pre-cancer, including tobacco smoking, hormonal ...
Parkkola, Hanna (Date of defense: 2014-12-01)
Novel stategies are needed to improve the limited efficacy of current cancer therapies. High expectations are directed towards nanotechnology-based applications in cancer medicine. We have developed a ...
Vegliante, Maria Carmela (Date of defense: 2013-09-26)
Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin lymphomas associated with poor prognosis and frequent relapses. Recently, the neuronal transcription factor SOX11 has been identified ...
Martínez Quetglas, Iris (Date of defense: 2018-01-09)
Insulin-like growth factor (IGF) signaling is frequently altered in HCC, including activation of IGF1R, IGF2 overexpression, IGFBP3 downregulation and IGF2R allelic losses1,2. A previous study from our ...
Recalde-Percaz, Leire (Date of defense: 2021-06-30)
Metastases are considered the last stage of tumour progression and the main cause of death associated to solid tumours. There are no effective treatments for metastasis which remain non- curable with ...
Bassani, Nicklas (Date of defense: 2017-12-15)
Antiangiogenic drugs are used clinically for treatment of different types of cancers and in the case of renal cell carcinoma (RCC) are now standard first-line treatments (Rini, 2009). Nevertheless, these ...
Yoldi, Guillermo (Date of defense: 2018-10-23)
The discovery that RANK signaling mediates the protumorigenic role of progesterone in the mammary gland and its association with poor prognosis in breast cancer has opened the possibility of using RANKL ...
Urruticoechea Ribate, Ander (Date of defense: 2008-01-29)
DE LA TESIS:<br/><br/>El cáncer primario de mama es un problema de salud de gran magnitud con una incidencia estimada de 1 de cada 10 mujeres. De entre los tratamientos sistémicos, el tratamiento hormonal ...