Mas-Ponte, David (Date of defense: 2022-11-14)
[eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic ...
Coll Iglesias, Laura (Date of defense: 2022-11-23)
[eng] Endometrial cancer represents the most common cancer arising from the uterine cavity and there is little hope for patients with recurrent or metastatic disease. Prior studies of our group reported ...
Lacy Oliver, Francisco de Borja de (Date of defense: 2021-06-22)
[eng] Colorectal cancer is a major global public health issue. According to the 2018 Global Cancer Statistics, 1.8 million new cases of colorectal cancer are diagnosed worldwide, with almost 900,000 ...
Fernández Martínez, Aranzazu (Date of defense: 2021-07-16)
[eng] HR-positive/HER2-negative (HR+/HER2-) is the most common breast cancer type, and it is a molecular heterogenic disease. This heterogeneity has direct prognostic and predictive implications in both ...
Montironi, Carla (Date of defense: 2022-06-20)
[eng] INTRODUCTION: Liver cancer is a devastating disease and represents the seventh most common cancer worldwide and the third leading cause of cancer-related death globally. Hepatocellular carcinoma ...
Diéguez Docampo, Andrea (Date of defense: 2023-03-02)
[eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient ...
Magaz Martínez, Marta (Date of defense: 2022-09-06)
[spa] Las enfermedades conocidas como minoritarias o raras son aquellas que afectan a una proporción muy baja de la población, en concreto a 5 personas de cada 10.000 habitantes. Aunque el número de ...
Bergamino Sirvén, Milana Arantza (Date of defense: 2022-11-29)
[eng] 80% of breast cancer (BC) express positive estrogen receptors (ER+) and up to 15% of them also overexpress or amplify the human epidermal growth factor receptor 2 (HER2), which confers a molecular ...
Garcia Mulero, Sandra (Date of defense: 2022-12-16)
[eng] Cancer is a heterogeneous disease, in which many cell types interact with cancer cells, forming a complex network. The crosstalk between the cancer cells and the immune microenvironment is determinant ...
Iannizzotto, Flavia (Date of defense: 2023-12-01)
[eng] MYC dysregulation is the most common alteration in cancers, driving several cellular processes that cooperatively promote aberrant cell growth and proliferation. Among them, the induction of protein ...