Ramponi, Valentina (Date of defense: 2024-03-15)
[eng] Anti-cancer therapies are based on the infliction of damage or stress to cancer cells, with the aim of triggering cell death. In practice, a fraction of cancer cells often evades cell death and ...
García Arroyo, Rocío (Date of defense: 2024-04-19)
[eng] Inherited Retinal Dystrophies (IRDs) are a clinically and genetically highly heterogeneous group of genetic pathologies characterized by progressive attrition of photoreceptor cells and other ...
Sánchez Bellver, Laura (Date of defense: 2023-12-15)
[eng] Ciliopathies encompass a broad group of heterogeneous inherited disorders associated with dysfunction of the cilium, a ubiquitous microtubule-based organelle that translates extracellular stimuli ...
Xiol Viñas, Clara (Date of defense: 2023-12-22)
[eng] Rett syndrome (RTT) is a severe neurodevelopmental disorder characterized by a regression in acquired skills, such as purposeful hand use and language, after an apparently normal early development. ...
Magallón Lorenz, Miriam (Date of defense: 2023-07-07)
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with ...
Dueso Barroso, Ana (Date of defense: 2024-04-11)
[eng] Cancer, a complex disease, arises from accumulated somatic genomic and epigenomic changes within tumor cells, typically acquired during an individual’s lifetime. These alterations confer growth ...
Salvadores Ferreiro, Marina (Date of defense: 2024-01-18)
[eng] Mutations exhibit an uneven distribution across the human genome, with a regional mutation density (RMD) influenced by chromatin landscapes and replication timing. While there is a good understanding ...
García Torre, Beatriz (Date of defense: 2024-04-26)
[spa] La molécula de ADN contiene toda la información necesaria para el desarrollo de los organismos vivos. El ADN se encuentra compactado en el núcleo de las células humanas, envuelto alrededor del ...