Solsona i Vilarrasa, Estel (Date of defense: 2021-03-22)
[eng] Cholesterol accumulation in mitochondrial membranes is a common feature of various chronic diseases, such as cardiovascular disease, cancer, and Alzheimer's as well as liver diseases. Studies prior ...
Peixoto, Francisca de Oliveira (Date of defense: 2017-09-05)
The correct timing of adult stem cell function is essential for tissue homeostasis. Our group was among the first to show that circadian rhythms segregate important stem cell functions along the day. ...
Matas Céspedes, Alba (Date of defense: 2016-11-28)
Follicular Lymphoma (FL) and Chronic Lymphocytic Leukemia (CLL) share several features in common: 1) they are indolent B-cell neoplasms, 2) patients usually relapse after treatment, 3) both pathologies ...
Cepeda, Edgar B. (Date of defense: 2015-12-18)
CXCR4 is a chemokine receptor originally discovered and cloned in leukocytes that functions by controling the migration to the inflammatory foci. The CXCR4 chemokine receptor and its ligand, SDF-1α (also ...
Montero Pérez, Núria (Date of defense: 2018-11-29)
The objectives of this thesis are to evaluate the strategies for expanding the donor pool by using expanded criteria donors and for increasing patient and graft survival by optimization of immunosuppression ...
Gomes Monteiro Lopes Baptista, Maria João (Date of defense: 2012-10-10)
Glucocorticoids are frequently included in the chemotherapy regimens administered to patients with CLL because they are potent immunosuppressant agents and because they are able to induce apoptosis in ...
Fornabaio, Giulia (Date of defense: 2023-04-14)
[eng] Living tissues are active materials with the ability to undergo drastic shape and dimension transitions. If properly controlled, these morphological changes allow various physiological phenomena ...
Prada Varela, Estela Maria (Date of defense: 2021-11-05)
Pediatric RMS is a developmental tumor that affects patients from birth to late adolescence. RMS tumorigenesis involves the stalk of embryological myogenic processes. Classically, two main subgroups of ...
Cuervo Requena, Guillermo (Date of defense: 2016-05-03)
En la presente tesis doctoral se estudia la problemática actual sobre la candidemia en el caso de pacientes adultos y se analizan las estrategias de manejo. En concreto, se aborda el estudio de utilidad ...
Catalán García, Marc (Date of defense: 2017-03-20)
Sporadic inclusion body myositis (sIBM) is the most common myopathy in elderly. This disease causes muscle wasting with both distal and proximal affectation. Quadriceps and finger flexors are muscle ...