Soriano Raya, Juan José (Date of defense: 2016-02-04)
Hachinski, Potter and Merskey introduced the term “leukoaraiosis” (from the Greek “leuko” = “white”, and “araiosis” = “rarefaction”) to designate bilateral and symmetrical areas in the white matter (WM) ...
Rabaneda Lombarte, Neus (Date of defense: 2019-07-22)
Neuroinflammation is present in practically all neurological disorders. Microglial cells, the main representatives of the endogenous immune system of the brain, play a key role in neuroinflammation, ...
Boyadjis, Melanie (Date of defense: 2021-06-04)
OBJECTIVES: Study the interdependence between stimulus duration and stimulus strength, to observe if by changing the stimulus duration, the current threshold levels will also change during pedicle screw ...
Pérez Salvia, Montserrat (Date of defense: 2019-03-01)
Cancer is considered nowadays a genetic and epigenetic disease. Aberrancies in epigenetic marks in DNA and histone tails together with alterations in epigenetic regulators responsible of catalyzing ...
Meca-Cortés, Oscar (Date of defense: 2014-12-17)
The transcription factor SOX2 is a key determinant of stem cell properties, also involved in the initiation, maintenance and progression of several human cancers. By studying the in ...
Shivalikanjli, Anu (Date of defense: 2021-04-06)
The broad objectives of this work are the identification of genes that contribute to the susceptibility to attention-deficit/hyperactivity disorder (ADHD) and cocaine dependence, two disorders that ...
Moles Meler, Ernest (Date of defense: 2015-12-09)
Bearing in mind the absence of an effective preventive vaccine against malaria (WHO, 2015) and its severe clinical manifestations that are principally associated with red blood cell (RBC) destruction ...
Parra Montes, Claudio (Date of defense: 2015-07-17)
En esta tesis se desarrolla una metodología general para la construcción tándem de manera asimétrica de importantes “building blocks” que se encuentran presentes en la estructuras de muchos productos ...
Lucariello, Mario (Date of defense: 2017-03-16)
STUDY I HYPOTHESIS Genetic alterations have already been recognized as major etiological factors for ASD and ID, of which RTT is an example. In addition to the contribution of polymorphic variants ...
Castells Sánchez, Alba (Date of defense: 2022-01-28)
Aging is a normal biological process characterized by a decline at molecular, brain and behavioral level with consequences on cognition and daily functioning. Lifestyle behaviors such as physical activity ...