Mostrando ítems 1-10 de 13
Solé Solé, Judith (Fecha de defensa: 2022-06-03)
Following the laws of evolution, bacteria are capable of slowly but inexorably acquiring resistance to antibiotic compounds that we have been using for decades. Therefore, bacteria that seemed harmless ...
Botteri, Gaia (Fecha de defensa: 2018-03-14)
Diabetes represents one of the biggest health challenges of the 21st century. Insulin resistance is the primary defect in the most common form of diabetes, type 2 diabetes mellitus (T2D), and is defined ...
Martínez Cartró, Míriam (Fecha de defensa: 2021-10-25)
Advances in structural and molecular biology have increased the knowledge of relevant and undrugged targets and have favoured the rational development of novel drugs through structure- based ...
Suñé Pou, Marc (Fecha de defensa: 2019-07-12)
Cationic Solid Lipid Nanoparticles (cSLNs) are one of the most promising nonviral vectors for gene therapy and DNA / RNA delivery. The aim of this thesis is the development and research of new formulations ...
Bagán Polonio, Andrea (Fecha de defensa: 2022-09-23)
The synthesis of heterocyclic organic compounds allows access to a wide arsenal of compounds with potential pharmacological activity. This Thesis is part of the field of pharmaceutical chemistry, ...
Ruiz García, Marta (Fecha de defensa: 2020-10-20)
In today’s society, people’s interest against health care is growing every day. On a health- concerned population, food supplements and nutraceuticals are products with an increasing interest among the ...
Pérez Areales, Francisco Javier (Fecha de defensa: 2017-07-14)
Alzheimer’s disease (AD) is the main neurodegenerative disorder and one of the most important health-care problems worldwide, because of its high prevalence and personal and economic impact. To aggravate ...
Amirthalingam, Ezhil (Fecha de defensa: 2018-10-01)
This thesis has its main focus on developing multi-functional nanomaterials, that we called nano- and microtools through two different approaches, top-down to provide support and bottom up to give ...
Limón Magaña, David (Fecha de defensa: 2017-07-21)
anostructured supramolecular hydrogels and gold nanoparticles, as two kinds of nanomaterials, were synthsized, characterized and evaluated for their potential as drug delivery systems. Two bis-imidazolium ...
Álvarez García, Daniel (Fecha de defensa: 2014-12-18)
Computer-aided drug design is a key player in current drug discovery projects. Structure-based computational approaches use the target structural information to suggest potentially active and safe drugs. ...