Garcia Garcia, Josep (Date of defense: 2016-07-04)
During the past years working in Ernest Giralt’s group, I’ve been involved in three different subprojects that constitute one of the three chapter of my thesis and have the same common link: the use of ...
Díaz Perlas, Cristina (Date of defense: 2018-03-07)
Peptides play a critical role in human physiology and harbour a huge potential as therapeutic agents. In this thesis, new peptides have been discovered as ligands for the epidermal growth factor (EGF) ...
Oller Salvia, Benjamí (Date of defense: 2015-05-18)
Brain delivery is a major unmet challenge because most drugs cannot cross the blood-brain barrier (BBB). Despite the restrictive nature of this barrier, brain vasculature reaches essentially every neural ...
Guixer, Bernat (Date of defense: 2014-03-31)
The blood-brain barrier (888) is a biological barrier that plays a crucial role protecting the brain from neurotoxic agents and regulating the influx and efflux of molecules required for the correct ...
Arranz Gibert, Pol (Date of defense: 2017-01-12)
The work of this thesis is based on research on peptides able to cross the blood-brain barrier and their use as tools to enable the delivery of drugs into the brain. The blood-brain barrier (BBB) is ...