Novoa Pardo, Eva Maria (Date of defense: 2012-12-20)
Gene translation is a central process in all cells, in which messenger RNA (mRNA) is decoded by the ribosome to produce a specific amino acid chain, that will later fold into an active protein. This ...
Iacobucci, Simona (Date of defense: 2021-03-18)
Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural ...
Gholami, Behjat (Date of defense: 2017-09-18)
Osteoporosis is a general skeletal disorder. It is characterized by a low bone mass and a microarchitectural deterioration of bone tissue, which increase bone fragility and susceptibility to fracture. ...
Chávez Martínez, Ángel de Jesús (Date of defense: 2020-12-22)
Los esteroles son una familia de compuestos triterpénicos que se presentan en forma libre (FS, por sus siglas en inglés) o conjugada, como ésteres (SE), glicósidos (SG) y acilglicósidos de esteroles ...
Rasti Zaghiyan, George (Date of defense: 2021-09-20)
The Sirtuin family of NAD+-dependent enzymes plays a key role in the maintenance of genome integrity upon stress. Sirtuins coordinate the response to different forms of stress at different levels and ...
Tamirlsa, Srlvldya (Date of defense: 2014-07-14)
La ciencia básica ha de engarzarse con las necesidades sociales. Así, nuestro laboratorio esta involucrado en identificar genes específicamente modulados durante el proceso de cicatrización mediante ...
Rivera Brugués, Núria (Date of defense: 2012-03-20)
Genomic microarray analysis is rapidly replacing conventional chromosome analysis by molecular karyotyping due to the significant increase in the power to detect causative CNVs. Here, we extensively ...
Castillo Andreo, David (Date of defense: 2023-03-01)
[eng] Microscopy and Chromosome Conformation Capture (3C) are the two main techniques for studying the three-dimensional (3D) organization of the genome. Microscopy, allowing the visualization of genomic ...
Turón Rodrigo, Gemma (Date of defense: 2019-04-25)
Colorectal tumors are not homogeneous entities but rather composed of a mixture of cells with different phenotypes, reminiscent of healthy intestinal epithelium cell types. Intestinal epithelium is one ...
Torruella i Cortés, Guifré (Date of defense: 2014-12-19)
To understand the origin of opisthokonts or infer evolutionary transitions within the group that contains two multicellular lineages (animals and fungi), it is first fundamental to understand the ...