Lorente Crivillé, Adriana (Date of defense: 2014-07-18)
Natural products from terrestrial plants and microorganisms have long been a traditional source of drugs. For centuries humans have been looking on their environment for medicines to treat illnesses. ...
Colom Sanmartí, Glòria (Date of defense: 2016-01-28)
In the course of this thesis, the optimal epitopes for the subsequent polyclonal rabbit antibody production for cTnI and NT-proBNP have been studied and chosen. cTnI and NT-proBNP are the most relevant ...
Garcia Garcia, Josep (Date of defense: 2016-07-04)
During the past years working in Ernest Giralt’s group, I’ve been involved in three different subprojects that constitute one of the three chapter of my thesis and have the same common link: the use of ...
López Asamar, Abraham (Date of defense: 2015-07-17)
Prolyl oligopeptidase (POP) is an 81-KDa bidomain enzyme which hydrolyses short proline-containing peptides. This enzyme is involved in mnemonic and cognitive processes, and the dysregulation of POP ...
Rocas Alonso, Pau (Date of defense: 2016-02-25)
This thesis, entitled "Multifunctional Self-stratified Polyurethane-Polyurea Nanosystems for Smart Drug Delivery" is structured as a compendium of publications, being organized around a methodological ...
Aiguabella Font, Nuria (Date of defense: 2014-02-07)
The Pauson-Khand reaction (PKR) is, formally, a [2+2+1] cycloaddition involving an alkene, an alkyne and a carbon monoxide molecule, typically mediated or catalyzed by a cobalt (0) complex. The product ...
Montagut Cañete, Enrique José (Date of defense: 2021-02-04)
The final goal of the thesis was to improve the diagnostic of infections caused by P. aeruginosa and S. aureus through a better understanding of the bacterial communication process known as Quorum Sensing ...
Gómez Santacana, Xavier (Date of defense: 2016-05-13)
Metabotropic glutamate receptors (mGlu receptors) are class C GPCRs widely distributed through the CNS and considered pharmacological targets for neurologic disorders, such as neuropathic pain and ...
Garcia Pindado, Júlia (Date of defense: 2017-05-12)
The present thesis is based on the development and optimization of a solid-phase strategy to prepare biaryl bicyclic pentapeptides. Suzuki-Miyaura cross-coupling reactions were used to obtain the biaryl ...
Paradís Bas, Marta (Date of defense: 2015-05-15)
The known as "difficult peptides", as well as those sequences that aggregate in solution, are some of those molecules with high applicability as nanomaterials or even in medicine field. This thesis has ...