Universitat de Barcelona
Now showing items 1-10 of 12
IL-12/IFN-γ axis is a principal pathway for intramacrophagic pathogens immunity such as leishmania or mycobacteria. Alterations in this axis, being both congenic (causing the primary immunodeficiency ...
Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder, characterized by progressive behavioral, motor and cognitive deficits (HDCRG, 1993; Ross & Margolis, 2001). The ...
Huntington’s disease is a progressive neurodegenerative disorder caused by the expansion of a CAG tract in the exon-1 of the huntingtin gene. Mutant huntingtin induces a large amount of toxic effects ...
Ulcerative colitis (UC) is an idiopathic chronic inflammatory disease of the large intestine. In most patients UC runs a remitting and relapsing course, with periods of active disease followed by phases ...
EN CATALÀ:<br/><br/>L'acceptació indefinida dels òrgans trasplantats mantenint el correcte funcionament de l'empelt sense necessitat d'administrar l'agressiu tractament immunosupressor constitueix el ...
The cell cycle, the group of processes involved in the duplication and division of a cell in two daughter cells is essential for all organism existence. The correct regulation of these processes is ...
Understanding the molecular underpinnings of neuronal dysfunction and degeneration involved in Huntington’s disease is a goal of increasing urgency for society and scientific community. In this Thesis ...
The striatum is one of the brain structures that controls body movement. In humans the striatum consists of two nuclei, the caudate and putamen which are separated by the internal capsule, while in mice ...
Diacylglycerol (DAG) is required for the generation of transport carriers at the Golgi complex. Several enzymatic reactions have been found to contribute to the maintenance of DAG levels at this organelle. ...
The quality of life of a significant proportion of IBD patients is poor as a result of persistent disease activity and repeated surgery, among others. Current treatments for Crohn’s disease are not able ...
