Now showing items 81-100 of 104
Zapata Corella, Pablo (Date of defense: 2022-09-19)
In the present thesis, analytical methods based on gas chromatography coupled with mass spectrometry, both single (GC-MS) or tandem (GC-MS/MS), have been developed and optimized for the detection and quantification of ...
Fabregat Palau, Joel (Date of defense: 2022-09-22)
Perfluoroalkyl substances (PFASs) and fluoroquinolone antibiotics (FQs) are pollutants of environmental interest due to their widespread presence in environmental compartments and their high toxicity and disrupting effects ...
Mas-Ponte, David (Date of defense: 2022-11-14)
[eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic mosaicism that composes ...
Martínez Prats, Raimon (Date of defense: 2022-11-17)
[eng] Remote high mountains allow the study of the environmental fate of legacy and emerging anthropogenic chemicals that form a worldwide diffuse background layer of pollution. Semi- volatile compounds like polychlorinated ...
Nicolini, Federica (Date of defense: 2022-12-02)
[eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. On the contrary, ...
Diéguez Docampo, Andrea (Date of defense: 2023-03-02)
[eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient and improve their ...
López Berbel, Martí (Date of defense: 2023-03-03)
[eng] Transition metal carbides (TMCs) have acquired a wide potential as a green chemistry catalysts. Their relatively high abundance and their catalytic performance makes them great candidates to replace scarce and pollutant ...
Privat Contreras, Cristian (Date of defense: 2023-04-20)
[eng] Intrinsically disordered proteins (IDPs) landed on the molecular biology framework at the turn of the 20th century to challenge the established protein function- structure paradigm. Due to their inherent flexibility ...
Hervés Carrete, Carmen (Date of defense: 2023-05-24)
[eng] The main objective of this dissertation has been to stablish a bridge between materials science and its fields of application. The scope of this thesis work, under this premise, is aimed towards understanding the ...
García Vara, Manuel (Date of defense: 2023-06-13)
[eng] This doctoral thesis aims at providing novel analytical tools for the environmental control of CECs in waters and crops and generating new knowledge about i) the occurrence and fate of CECs in the agricultural ...
Jurado Mañas, Anabel (Date of defense: 2023-06-21)
[eng] MXene materials, the low-dimensional counterpart of transition metal carbides and nitrides present suitable properties as catalysts in heterogeneous catalysis given the similar properties with transition metal carbides ...
López Olivé, Maria (Date of defense: 2023-09-15)
[spa] Los estudios sobre exposición a nanopartículas (NP) en aerosoles atmosféricos son cada vez más importantes para comprender sus efectos en la salud humana y el medio ambiente, ya que las NP pueden penetrar profundamente ...
Loren Parrondo, Guillem (Date of defense: 2023-09-15)
[eng] In this doctoral thesis, the design and synthesis of bifunctional molecules that induce the degradation of a target protein in cells are described. The synthesis of molecules capable of inducing the phosphorylation ...
Magkanas, Georgios (Date of defense: 2023-09-18)
[eng] The present PhD thesis is focused on the study of the compositional, morphological and formal characteristics of medieval cultural heritage objects, and more specifically manuscripts and champlevé enamels of Limoges, ...
Vaz, Rodolpho Fernando (Date of defense: 2023-10-27)
[eng] Additive manufacturing (AM) is a process of creating a physical object by adding material layer by layer rather than removing material through machining. It is also known as 3D printing, as it typically involves using ...
Lozano Reis, Pablo (Date of defense: 2023-11-10)
[eng] Global warming and climate change, mostly due to the increasing concentration of greenhouse gases in the atmosphere, are producing devastating effects. Among the different greenhouse gases, CO2 is one of the major ...
Subirana Granés, Marc (Date of defense: 2023-11-17)
[eng] Historically, cancer genomics has predominantly focused on coding regions. Current knowledge suggests that non-coding mutations are likely crucial in driving the mechanisms that regulate gene activity, potentially ...
Barazorda Ccahuana, Haruna Luz (Date of defense: 2023-11-17)
[eng] Computational simulation technologies facilitate the resolution of complex biomedical problems by helping researchers predict what will happen in a natural system in response to various external conditions. The main ...
Otero Rodríguez, Ana Mª (Date of defense: 2023-11-28)
[eng] Meat industry and particularly pig slaughterhouses produce huge amounts of animal by- products not intended for human consumption. This residual stream appears as a potential raw material for anaerobic digestion and ...
Gómez García, Roberto (Date of defense: 2023-12-15)
[spa] La presente Tesis de carácter multidisciplinar se centra en el diseño y síntesis de nuevos derivados de C75 como potenciales agentes antitumorales e inhibidores de la ingesta para el desarrollo de nuevos fármacos ...