Universitat de Barcelona
Now showing items 24-43 of 101
Pain is one of the main medical problems that in several cases results into a chronic disease with limited effective treatment, thus the discovery of new drugs to fight against constitutes a big challenge nowadays. Metabotropic ...
The main objective of this research work was to produce environmentally friendly cermets coatings, Ni and Co free matrix, alternative to conventional WC- Co, by thermal spray processes. WC-Co cermets has always been one ...
Se han obtenido distintas aleaciones policristalinas de base cobre así como monocristalinas de ZuCnAlCo, las cuales han sido caracterizadas quimícamente, estructural y calorimétricamente. Se ha utilizado un nuevo método ...
[spa] La presente Tesis de carácter multidisciplinar se centra en el diseño y síntesis de nuevos derivados de C75 como potenciales agentes antitumorales e inhibidores de la ingesta para el desarrollo de nuevos fármacos ...
En aquesta Tesi s’han estudiat les fonts d’emissió de diversos contaminants atmosfèrics, principalment a l’àrea de Barcelona. Els contaminants estudiats han estat l’òxid de nitrogen (NO), compost tòxic que s’emet en grans ...
[eng] In this doctoral thesis, the design and synthesis of bifunctional molecules that induce the degradation of a target protein in cells are described. The synthesis of molecules capable of inducing the phosphorylation ...
The general objective of this research was the design of polymeric cationic nanoparticles from nano-emulsions obtained by low-energy methods for biomedical applications. This general objective includes the preparation of ...
[eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. On the contrary, ...
[eng] The main objective of this dissertation has been to stablish a bridge between materials science and its fields of application. The scope of this thesis work, under this premise, is aimed towards understanding the ...
Chemical exposure to emerging contaminants (ECs) is a major concern nowadays. These ECs have recently become a global environmental threat, and an in-depth characterization of their occurrence and toxic impact is needed. ...
Nuclear Magnetic Resonance (NMR) spectroscopy is able to produce by a single direct measurement a very high amount of chemical information. However, this information is not always easy to interpret. In fact, the complexity ...
Modern medical treatments are largely based on the ability of pharmacological drugs to interact with a molecular target in the human body (e.g., receptors) in order to evoke a physiological response. Such targets are ...
Photopharmacology is an emerging field that relies on the development of photosensitive compounds to enable precise spatiotemporal control over endogenous proteins. Photochromic ligands· are designed to respond ...
Perfluoroalkyl substances (PFASs) are a large group of man-made chemicals that are widely used throughout society and found in the environment. These compounds are characterized by perfluorinated carbon chains of varying ...
Dynamic combinatorial chemistry proposes the creation of a library of compounds (dynamic combinatorial library, DCL) inter-connected through reversible chemical processes. The concentrations in a DCL are determined by ...
En esta tesis doctoral se han desarrollado tres metodologías analíticas para el análisis de drogas, psicofármacos y sus metabolitos en tres compartimentos medioambientales: aguas residuales, sedimentos y biota. Las ...
Les drogues d'abús i els fàrmacs estan considerats com contaminants d'interès emergent en el medi aquàtic, és a dir, són substàncies que no estan incloses en els programes habituals de control i monitorització d'aigües, ...
La presencia de substàncies d’origen antropogènic en el medi aquàtic és un de les fites importants a les que actualment s’ha d’enfrontar la química ambiental. En la darrera dècada les drogues d’abús s’han sumat al conjunt ...
The increased presence of nano-enabled products in multiple applications has raised concerns about its potential risks to human health and the environment. Therefore, there is a need for a responsible and coordinated ...
En los últimos años, los contaminantes emergentes (ECs) están recibiendo una creciente atención debido a los efectos nocivos que suponen para los organismos vivos y al riesgo ambiental que representan. Existen una gran ...
