Facultat de Química: Enviaments recents
Ara mostrant els elements 61-80 de 103
L'alcohol terc-butílic com a solvent d'interés analític: equilibris protolítics i les seves aplicacions
L’objecte primordial del present treball ha estat l’estudi teòric i pràctic d’un solvent, l’alcohol terc-butílic, que tot i essent un dels solvents més semblants a l’aigua, presenta respecte a ella notables diferències. ...
Desarrollo y caracterización del efecto doble memoria de forma obtenido mediante martensita estabilizada en aleaciones base cobre y de la fenomenología de envejecimiento
Se han obtenido distintas aleaciones policristalinas de base cobre así como monocristalinas de ZuCnAlCo, las cuales han sido caracterizadas quimícamente, estructural y calorimétricamente. Se ha utilizado un nuevo método ...
Structural characterization of amyloid beta oligomers with functional links associated to Alzheimer's disease
Alzheimer’s disease (AD) is the most common form of dementia. It was first described in 1906 by Alois Alzheimer. Later on, in 1984 George Glenner and Colin Masters isolated the amyloid-beta (Aβ) peptide from a human brain ...
Deposition of environmentally friendly cermets coatings by thermal spray techniques
The main objective of this research work was to produce environmentally friendly cermets coatings, Ni and Co free matrix, alternative to conventional WC- Co, by thermal spray processes. WC-Co cermets has always been one ...
Simulación de una columna de paredes mojadas como reactor de sulfonación
Este trabajo se ha concebido como continuación de otros anteriores, realizados en el Departamento de Química Técnica de la Facultad de Química de la Universidad de Barcelona, sobre sulfonación con SO(3) vapor en reactor ...
Utilització de 9-fluorenilmetoxicarbonilaminoàcids a la síntesi en fase sòlida de segments peptídics protegits
L'objectiu principal d'aquesta Tesi és posar a punt una metodologia de síntesi en fase sòlida de segments peptídics protegits, la qual cosa comporta l´engalzament successiu dels aminoàcids sobre el suport sòlid, el ...
3d and/or 4f coordination compounds derived from chiral Schiff bases: magnetic and spectroscopic study
This PhD thesis has been developed in the Molecular Magnetism Group of the University of Barcelona. As its name indicates, the Molecular Magnetism Group is mostly interested in the magnetic study of coordination complexes, ...
Information Transfer and Dynamics of Nucleic Acids studied by Theoretical Approaches
1. The Force Field Accuracy Problem. The utility and applicability of MD simulations to model biomolecular systems goes only as far as its ability to sufficiently sample the conformational space and the correct description ...
Non-glycosidic analogues of alpha-galactosylceramide: Design, synthesis and biological activity
The Immune System (IS) is a complex collection of tissues, organs, cells and molecules to defense the body against threatens. IS is organized into two lines of defense: innate immunity which acts in a non-specific manner ...
Development and application of Nuclear Magnetic Resonance spectroscopy and chemometric methods for the analysis of the metabolome of Saccharomyces cerevisiae under different growing conditions
Nuclear Magnetic Resonance (NMR) spectroscopy is able to produce by a single direct measurement a very high amount of chemical information. However, this information is not always easy to interpret. In fact, the complexity ...
Towards the validation of a druggable amyloid-beta oligomer as a target for Alzheimer´s disease = Cap a la validació d’un oligomer de beta-amiloide com a diana en la malaltia d’Alzheimer
Amyloid-beta peptide (Aβ) is strongly linked to the aetiology of Alzheimer’s disease (AD). Aβ is the main component of the amyloid plaques found in the brain of AD patients, however, Aβ is also present in the brain of ...
Synthesis of Sonic Hedgehog protein and development of peptide binders using phage display libraries
Chemical protein synthesis has become a potent tool for the synthesis of proteins, especially those which are not easily accessed by DNA recombinant methods, such as proteins with posttranslational modifications. The key ...
Assessment of the lipidomic effects of environmental pollutants on exposed organisms using chemometric and analytical methods
Lipidomics is a subset of metabolomics, which in turn, is one of the categorical platforms that constitute omics. Omic sciences aim at the study of the abundance and (or) structural characterization of a broad range of ...
Studies toward the synthesis of marine natural products Phormidolides B-D
Marine natural products (MNPs) are, undoubtedly, highly valuable starting points for drug-development programs. Generally, MNPs show a well-defined spatial orientation that have evolved for thousands of years to interact ...
Estudi de molècules orgàniques fòssils per a la caracterització dels esdeveniments climàtics ocorreguts durant períodes glacials i interglacials
Arribar a comprendre les causes i efectes dels canvis globals i les interaccions sinèrgiques del sistema climàtic continua sent un repte científic complex. Els informes del Panell Intergovernamental sobre el Canvi Climàtic ...
Deciphering the role of peripheral and central nervous system metabotropic glutamate receptors in neuropathic pain with photoactivable ligands
Pain is one of the main medical problems that in several cases results into a chronic disease with limited effective treatment, thus the discovery of new drugs to fight against constitutes a big challenge nowadays. Metabotropic ...
Identification and Fate of Known and Unknown Transformation Products of Pharmaceuticals in the Aquatic System
Pharmaceuticals which are used worldwide are designed to facilitate the life for the human society and have an important role in treatment and prevention of disease for both humans and animals. They are ubiquitous in the ...
Indole arylation in tryptophan residues: development of new chemical methodologies, synthetic studies and biological evaluation of modified peptides
In the present thesis we have investigated the development of new methodologies for the selective and straightforward chemical modification of Trp amino acid either alone or in peptides. In the first chapter, we have ...
Mecanismo cinético de la xantinoxidasa de hígado de buey y de la xantindeshidrogenasa de hígado de pollo
La xantinoxidasa (xantina: oxígeno-oxidorreductasa) fue descubierta por HORBACZEWSKI y SPITZER al observar que la hipoxantina y la xantina, en presencia de varios preparados tisulares, daban lugar a la aparición de ácido ...
Drogues en el medi aquàtic: de les aigües residuals a l’aigua potable
La presencia de substàncies d’origen antropogènic en el medi aquàtic és un de les fites importants a les que actualment s’ha d’enfrontar la química ambiental. En la darrera dècada les drogues d’abús s’han sumat al conjunt ...
