Mostrando ítems 21-40 de 105

    Exploring protein structure changes due to somatic mutations in cancer 

    Diéguez Docampo, Andrea (Fecha de defensa: 2023-03-02)

    [eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient and improve their ...

    Design of peptides able to modulate Protein-protein interactions (PPIs) in mutated p53 

    Nicolini, Federica (Fecha de defensa: 2022-12-02)

    [eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. On the contrary, ...

    Passive air and water sampling in high-altitude lakes: occurrence and distribution of legacy and emerging organic pollutants 

    Martínez Prats, Raimon (Fecha de defensa: 2022-11-17)

    [eng] Remote high mountains allow the study of the environmental fate of legacy and emerging anthropogenic chemicals that form a worldwide diffuse background layer of pollution. Semi- volatile compounds like polychlorinated ...

    Localized hypermutation and hypomutation in the genomes of human somatic cells 

    Mas-Ponte, David (Fecha de defensa: 2022-11-14)

    [eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic mosaicism that composes ...

    Occurrence and distribution of organochlorinated pesticides and flame retardants in Spain and China 

    Zapata Corella, Pablo (Fecha de defensa: 2022-09-19)

    In the present thesis, analytical methods based on gas chromatography coupled with mass spectrometry, both single (GC-MS) or tandem (GC-MS/MS), have been developed and optimized for the detection and quantification of ...

    Sorption of perfluoroalkyl substances and Fluoroquinolone antibiotics in matrices of environmental interest 

    Fabregat Palau, Joel (Fecha de defensa: 2022-09-22)

    Perfluoroalkyl substances (PFASs) and fluoroquinolone antibiotics (FQs) are pollutants of environmental interest due to their widespread presence in environmental compartments and their high toxicity and disrupting effects ...

    Development and application of analytical and chemometric methodology for environmental metabolomic studies based on one-and two-dimensional liquid chromatography coupled to mass spectrometry 

    Pérez Cova, Miriam Carolina (Fecha de defensa: 2022-09-05)

    Chemical exposure to emerging contaminants (ECs) is a major concern nowadays. These ECs have recently become a global environmental threat, and an in-depth characterization of their occurrence and toxic impact is needed. ...

    Primary batteries paradigm redefinition within the environmental planetary boundaries 

    Navarro-Segarra, Marina (Fecha de defensa: 2022-07-27)

    Digital technologies are generating a global transformation with economic, social, and environmental implications. Digitalization has already shown many benefits to society; however, it is also generating a fierce debate ...

    The Antarctic as Sentinel of Global Pollution 

    Casas Papell, Gemma (Fecha de defensa: 2022-07-19)

    Since the industrial revolution, we have introduced thousands or tens of thousands of new synthetic compounds, originating a new environmental perturbation in the Earth’s system. Among these, there are the so-called ...

    Estudio de la tostación de los seleniuros de plata (Ag2Se), de cobre (I) (Cu2Se) y de plata y cobre (AgCuSe), en atmósfera de aire 

    Segarra Rubí, Mercè (Fecha de defensa: 1994-01-01)

    Los lodos anódicos del afino electrolítico del cobre contienen grandes cantidades de selenio, la mayor parte del cual se encuentra presente en forma de seleniuros de plata y cobre. Para recuperar la plata, el cobre y el ...

    Síntesis del fragmento 1-4 de la toxina II del escorpión "Androctonus australis hector". Estudio de la n-benzhidril-(4-brometil-3-nitro) benzoilamida como modelo monimérico del α-(4-bromometil-3-nitrobenzamido)benzilpoliestireno 

    Nicolás Galindo, Ernesto (Fecha de defensa: 1988-01-01)

    Como se puede comprobar por la cantidad de ejemplos que se han descrito y siguen describiéndose en la literatura, la síntesis en fase sólida se ha erigido como un método extremadamente eficaz para la obtención de péptidos ...

    Síntesis y estudio de clusters de elementos metálicos con una nuclearidad máxima de cuatro 

    Ferrer García, Montserrat (Fecha de defensa: 1989-01-01)

    En el Departamento de Química Inorgánica de la Universidad de Barcelona se está desarrollando desde 1984 una línea de investigación que tiene como objeto la síntesis de compuestos con enlace metal-metal en la que uno de ...

    Preparación y reactividad de compuestos organometálicos de platino de tipo [PtXR (PPh3)2] (X=HgR' o H) 

    Crespo Vicente, Margarita Ma. (Fecha de defensa: 1986-01-01)

    Paralelamente al desarrollo de la Química Organometálica, se ha producido un notable, y en ocasiones espectacular, avance en el campo de los hidruro-complejos en el que el platino ha desempeñado un papel destacado, siendo ...

    Estudi comparatiu de les reaccions d'anionització, en estat sòlid, d'aquo-complexos de crom (III) amb diverses amines: en, tmd, chx i mixtes 

    Corbella i Cordomí, Montserrat (Fecha de defensa: 1986-01-01)

    En aquesta Tesi s'ha volgut veure l'efecte del volum dels lligands i dels anions (que varien l'espai lliure) en l'energia d'activació. Per arribar a conclusions rigoroses caldria tenir les estructures cristal·lines i ...

    Bioactive glass coatings obtained by thermal spray techniques 

    Garrido Domínguez, Beatriz (Fecha de defensa: 2022-06-22)

    Bone tissue has an excellent healing response, recovering functional and structural properties when damaged. Notwithstanding, severe damage to the bone implies the need for surgery to recover. Different orthopaedic devices ...

    Computational Analyses of CO2 Electroreduction and C Interactions with Transition Metals 

    Piqué Caufapé, Oriol (Fecha de defensa: 2022-05-03)

    Catalysis is ubiquitous in chemical industries since it accelerates chemical reactions, thereby saving considerable amounts of energy. Most catalytic processes in industry are heterogeneous in nature, typically involving ...

    Technical and economic evaluation of anaerobic membrane bioreactors for municipal wastewater treatment 

    Vinardell Cruañas, Sergi (Fecha de defensa: 2022-05-04)

    Anaerobic membrane bioreactor (AnMBR), which is a combination of membrane separation and anaerobic digestion, is an emerging biotechnology for municipal sewage treatment. The application of AnMBRs in the mainline of ...

    Ti-containing hybrid organosilicas, Mo(x)C/g-C(3)N(4) nanocomposites and engineered Mo(x)C/TiO(2) nanomaterials as noble-metal-free photocatalysts for H(2) production 

    Wang, Yan (Fecha de defensa: 2022-04-07)

    The photocatalytic hydrogen production is considered an environmentally promising and friendly method, which could lead to achieve clean and renewable hydrogen and contribute in the future to store solar energy as chemical ...

    Actividad de la proteina intrínsecamente desordenada p15(PAF) en el replisoma o cómo el desorden orquesta la replicación celular 

    Barrera Vilarmau, Susana (Fecha de defensa: 2022-03-15)

    La abrazadera deslizante eucariota (PCNA), juega un papel esencial como componente del replisoma. PCNA, de forma toroidal, rodea el DNA y ata las polimerasas y otros factores a la plantilla genómica para una síntesis ...

    Advanced Modelling of Metallic Nanomaterials for Catalysis 

    Vega Domínguez, Lorena (Fecha de defensa: 2021-12-21)

    Nanoparticles are highly relevant for catalysis due to their nanostructure, which increases the fraction of surface atoms, and the size dependent morphology and properties. Catalytic properties of nanoalloys also depend ...