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The first 3D structural model of an eukaryotic heteromeric aminoacid transporter / Primer model estructural en 3D d’ un transportador heteromèric d’aminoàcids eucariota 

Costa i Torres, Meritxell (Date of defense: 2012-05-04)

Introduction Heteromeric amino acid transporters (HATs) are composed of a heavy subunit (rBAT or 4F2hc) and a light subunit (b0 + AT, ASC1, LAT1, LAT2, y + LAT1, y + LAT2 and xCT), joined by a disulfide ...

Modulation of adenosine A(2A) receptor function by interacting proteins. New targets for Huntington’s disease / Modulación de las funciones del receptor A2A de adenosina por interacción con otras proteínas. Nuevas dianas para la enfermedad de Huntington. 

Bakešová, Jana (Date of defense: 2012-06-01)

In this dissertation we studied the pharmacological and functional consequences of adenosine A2A receptor interaction with other proteins, as other neurotransmitter receptores localized in the human ...

The Role of the Cell Cycle in Human Embryonic Stem Cell Self-Renewal and Pluripotency (La función del ciclo celular en la auto-renovación y la pluripotencia de las células madre embrionarias humanas) 

Menchon Najas, Cristina (Date of defense: 2011-06-09)

Embryonic stem cells (ESC) are derived from the inner cell mass (ICM) of the blastocyst and have the capacity for unlimited proliferation while retaining their potential to differentiate into a wide ...

Anàlisi in silico de malalties: des de les mutacions fins les xarxes biològiques 

Porta Pardo, Eduard (Date of defense: 2013-03-05)

In the era of “omics” data, the use of computational approaches to store, integrate and analyze biological information is becoming a priority, particularly in the field of biomedicine and the study of ...

Role of Methylation in Modulating MAPK Signaling. Implications in Melanoma. Papel de la metilación como modulador de la señalización en MAPK. Implicaciones en melanoma. 

Andreu Pérez, Pedro Antonio (Date of defense: 2012-03-12)

1. General Overview MTAP is a key enzyme in the methionine salvage pathway and controls the levels of methylthioadenosine (MTA). Lost of MTAP, which is frequent in melanoma, results in higher intra and ...

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577 - Biochemistry. Molecular biology. Biophysics (4)

575 - General genetics. General cytogenetics. Immunogenetics. Evolution. Phylogeny (1)

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Open access (5)

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