Universitat de Barcelona
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Cachexia SCOre (CASCO) es una nueva herramienta cuantitativa para la clasificación de la caquexia cancerosa en pacientes. La escala incluye cinco componentes: 1) pérdida de peso y composición corporal, ...
Cancer is one of the leading causes of death in countries throughout the world. Increase in the production of Reactive Oxygen Species (ROS) has been implicated in many human disease processes, including ...
Angiogenesis is the formation of blood vessels from the pre-existing ones and is required for distributing nutrients and oxygen to the tissues through the blood flow. This process is important for tumour ...
During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical ...
Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear ...
Cancer is characterised by the lost of physiological control and the malignant transformation of cells that acquire functional and genetic abnormalities, leading to tumour development and progression. ...
La Tesi Doctoral porta per títol "CONTROL DE PROTEÏNES REGULADORES DE L'APOPTOSI EN CÈL·LULES LEUCÈMIQUES", i ha estat realitzada a la Unitat de Bioquímica del Departament de Ciències Fisiològiques II ...
Voltage dependent potassium channels are a group of plasma membrane ion channels with a key role in the immune system as the predominant ion channels controlling the resting membrane potential and tuning ...
In this thesis, tumor metabolic reprogramming has been exploited in order to propose new targets in cancer treatment. On one hand, we explored the pentose phosphate pathway (PPP) enzymes as putative ...
The present doctoral thesis is focused on the metabolic adaptations induced by oncogene activation as well as the potential role of the metabolic network as antitumor therapy. Over the last years, it ...
