Tarrado Castellarnau, Miriam Neus (Date of defense: 2015-12-11)
Cancer is characterised by the lost of physiological control and the malignant transformation of cells that acquire functional and genetic abnormalities, leading to tumour development and progression. ...
Aguilar Fadó, Esther (Date of defense: 2015-02-23)
Metastasis represents the most life-threatening aspect of tumorigenesis and is the leading cause of death by cancer. Intensive research in this field has shed light on some of the molecular strategies ...
Sánchez Tena, Susana (Date of defense: 2012-07-27)
La present Tesi Doctoral es centra en l'estudi de l'efecte de diferents compostos d'origen natural sobre el càncer de còlon. La Tesi s'estructura en dues parts: la primera in vitro basada en estudis amb ...
Carreras Cardona, Anna (Date of defense: 2012-05-04)
During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical ...
Cortés Giràldez, Roldàn (Date of defense: 2014-07-30)
El propósito de esta Tesis Doctoral es el de explorar nuevas posibilidades de tratamiento y de diagnóstico del cáncer de pulmón, y concretamente del cáncer de pulmón no microcítico de células con ...
Polat, Ibrahim H. (Date of defense: 2016-11-04)
In this thesis, tumor metabolic reprogramming has been exploited in order to propose new targets in cancer treatment. On one hand, we explored the pentose phosphate pathway (PPP) enzymes as putative ...
Marín de Mas, Igor Bartolomé (Date of defense: 2015-03-20)
The general aim of this thesis is to develop and apply new computational tools to overcome existing limitations in the analysis of metabolism. This thesis is focused on developing new computational ...