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Functional studies of 4F2hc-CD147 interaction = Estudios funcionales de la interacción 4F2hc‐CD147 

Delgado Martin, Gonzalo (Date of defense: 2014-07-14)

We identified proteins that interacted with the ectodomain of 4F2hc, a plasma membrane protein with dual function as heavy subunit of the amino acid transporters and positive regulator of β1 and β3 ...

New insights into carotenoid accumulation in tomato fruit = Nuevos aspectos sobre acumulación de carotenoides en el fruto del tomate 

Pourcq, Karel de (Date of defense: 2014-01-24)

Lycopene is an antioxidant carotenoid present in high amounts inside the ripe tomato fruit, in watermelon, red bell pepper and a few other red-pigmented fruits. Its health benefits, notably the prevention ...

A novel role for glycogenin in the regulation of glycogen metabolism 

Testoni, Giorgia (Date of defense: 2016-02-05)

Glycogen synthesis is crucial for storing glucose residues that are released in case of energy demand. The mechanism needs to be tightly regulated because a lack or an overload of glycogen can lead to ...

Deciphering the interaction between Kvl.3 and Caveolin 

Pérez Verdaguer, Mireia (Date of defense: 2015-01-26)

The voltage-dependent K+ channel Kv1.3 participates in many physiological events like proliferation and activation of immunitary cells, membrane repolarization in sensory neurons, vascular smooth muscle ...

Characterization of endothelial cell metabolism under different microenvironmental challenges: exploring therapeutic implications of targeting glycogen degradation 

Jayaraman, Anusha (Date of defense: 2016-07-05)

Angiogenesis is the formation of blood vessels from the pre-existing ones and is required for distributing nutrients and oxygen to the tissues through the blood flow. This process is important for tumour ...

Study of the Electron-Transfer properties of phenolics and their relationship with the biological activity on cancer cells 

Carreras Cardona, Anna (Date of defense: 2012-05-04)

During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical ...

Role of DOR/TP53INP2 in the control of muscle protein degradation = Papel de DOR/TP53INP2 en el control de la degradación de proteínas en el músculo esquelético 

Martinez Cristobal, Paula (Date of defense: 2016-12-01)

Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear ...

Structural studies of Heteromeric Amino acid Transporters (HATs): Validation of the first 3D structural model of a HAT (human 4F2hc/LAT2) and identification of new HAT targets for 3D‐crystallization 

Álvarez Marimón, Mª Elena (Date of defense: 2014-10-27)

Heteromeric amino acid transporters (HATs) mediate the transport of amino acids through the plasma membrane. They are composed of two subunits (a heavy and a light one) linked by a conserved disulfide ...

Molecular studies of two methylerythritol 4-phosphate pathway enzymes of isoprenoid biosynthesis : the 4-diphosphocytidyl-2C-methyl-D-erythritol kinase and the 1-deoxy-D-xylulose 5-phosphate synthase = Estudios moleculares de dos enzimas de la ruta del metileritritol 4-fosfato de biosíntesis de isoprenoides : la 4-difosfocitidil-2C-metil-D-eritritol quinasa y la 1-dexosi-D-xilulosa 5-fosfato sintasa 

Giménez Oya, Víctor (Date of defense: 2009-12-09)

Los isoprenoides son una de las mayores familias de compuestos descritos en la naturaleza. Estos compuestos están presentes en todos los organismos vivos y se sintetizan a partir de dos moléculas de 5 ...

4F2hc/LAT1 heterodimer: a promising candidate for solving the first atomic structure of a heteromeric amino acid transporter = Heterodímero 4F2hc/LAT1: un candidato prometedor para resolver la primera estructura atómica de un transportador heteromérico de aminoácidos 

Obando Martínez, Ana Zuleima (Date of defense: 2016-05-19)

Heteromeric amino acid transporters (HATs) are the unique solute transporters known to be composed of two subunits linked by a disulphide bridge. The heavy subunit (4F2hc or rBAT), a type II membrane ...

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Cascante i Serratosa, Marta (6)

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Fernández-Recio, Juan (2)

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2020 - 2024 (2)

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Ciències Experimentals i Matemàtiques (34)

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577 - Biochemistry. Molecular biology. Biophysics (34)

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Open access (33)

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