Aguilar Fadó, Esther (Date of defense: 2015-02-23)
Metastasis represents the most life-threatening aspect of tumorigenesis and is the leading cause of death by cancer. Intensive research in this field has shed light on some of the molecular strategies ...
López Fauqued, Marta (Date of defense: 2010-06-22)
Malignant melanoma is the most lethal skin cancer with no effective therapeutic treatment in its metastatic stages. RAS and PI3K pathways have been shown to play a critical role in melanoma development ...
Benito Mauricio, Adrián (Date of defense: 2014-02-21)
The present doctoral thesis is focused on the metabolic adaptations induced by oncogene activation as well as the potential role of the metabolic network as antitumor therapy. Over the last years, it ...