Mostrando ítems 100-113 de 113
González-Ortega, Emmanuel (Fecha de defensa: 2012-07-23)
There are several reasons to celebrate the latest advances in the treatment of the infection with HIV. According to the Joint United Nations Programme on HIV/AIDS, the number of new infections dropped by 15%; there is also ...
Sebastián Muñoz, David (Fecha de defensa: 2006-03-31)
La resistencia a la insulina es un estado patológico que se define como la incapacidad del organismo de responder normalmente a las acciones de la insulina. Este estado está ligado a la obesidad, al estilo sedentario de ...
Robert Moreno, Alexandre (Fecha de defensa: 2007-09-28)
The process that gives rise to all the mature blood cells from the HSCs (Hematopoietic Stem Cells) is known as hematopoiesis. In the adult, hematopoiesis takes place in the bone marrow although the HSCs are likely generated ...
Sdelci, Sara (Fecha de defensa: 2012-12-13)
This thesis project is focused on the study of the signaling module formed by the NIMA-related protein Nek6, Nek7, and Nek9 and their function during early mitosis, with particular interest in centrosome separation and ...
Pulice, Giuseppe (Fecha de defensa: 2014-12-15)
Changes in diet and life style caused an alarming increase in the incidence of obesity, which is considered a major risk factor for the onset of the metabolic syndrome. One of the initial events in obesity is adipocyte ...
Kaczmarska, Zuzanna (Fecha de defensa: 2014-12-05)
Picornaviridae are among the most diverse and oldest known viral families that include many important pathogens of humans and animals. They are small, icosahedral (+)ssRNA viruses, causing a variety of diseases, such as ...
Quiles Vidal, Francisco de Asís (Fecha de defensa: 2016-02-05)
ANTECEDENTES: Entre un 20-25% de pacientes con cáncer de mama y ovario muestran historia familiar de dicha enfermedad. Una porción de estos casos son debidos a mutaciones germinales en genes de predisposición conocidos y ...
dos Reis Mendes, Soraia Inês (Fecha de defensa: 2022-10-28)
[eng] Several proteases and their antagonistic protein or peptide inhibitors sparked researchers’ interest due to their potential as therapeutic targets. The present thesis, which compiles results obtained in three independent ...
Malandrino, Maria Ida (Fecha de defensa: 2013-10-04)
Current lifestyle with high-energy diets and little exercise is triggering an alarming growth in obesity. Excess of adiposity is leading to severe increase in associated pathologies, such as insulin resistance, type ...
Meo Evoli, Nathalie (Fecha de defensa: 2014-07-07)
The oncogenic properties of E2F1 have been traditionally associated with the role of the oncogene in proliferation, but during the last few years many other functions associated with this family of transcription factors ...
Bertran Domingo, M. Teresa (Fecha de defensa: 2012-11-29)
Nek9 is a NIMA-related kinase that is phosphorylated in mitosis and a small pool of it (5%) is activated at the centrosomes by a complex mechanism which has remained elusive until now. Nek6 and Nek7 bind to the C-terminal ...
Carrasco Rodríguez, Patricia (Fecha de defensa: 2012-03-16)
Carnitine palmitoyl transferase 1 (CPT1) enzymes catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, thus facilitating the entry of long-chain fatty acids to the mitochondria, where they undergo β-oxidation. ...
Alonso Tarajano, Manuel Alejandro (Fecha de defensa: 2013-10-24)
In human there are 518 protein kinases reported and many of them are involved in several cellular processes and also in important pathologies. Kinases have a diverse specificity for the sequences they phosphorylate, and ...
Tnani, Hédia (Fecha de defensa: 2012-07-18)
The embryo in grasses, at grain maturity, comprises the embryonic axis and the scutellum. The scutellum is supposed to be the single cotyledon in the monocotyledoneus embryos and is attached to the embryo axis in the ...