Ara mostrant els elements 21-30 de 31
Ventura Ventanachs, Verònica (Data de defensa: 2013-10-18)
Irosustat is a first-generation, irreversible, steroid sulfatase inhibitor currently in development for hormone-dependent cancer therapy. Its structure is a tricyclic coumarin-based sulfamate that ...
Robles García, Virginia (Data de defensa: 2014-12-05)
Clathrin is an evolutionary conserved molecule that coats membranes endocytosed from the plasma membrane and those that move between the trans-Golgi network (TGN) and endosomes of eukaryotic cells. It ...
Rojas Expósito, Luis Alfonso (Data de defensa: 2017-05-26)
Cancer virotherapy with oncolytic adenoviruses represents a promising therapeutic approach due to the capacity of these viruses to infect and selectively kill tumor cells without damaging normal tissues. ...
Rodríguez Banqueri, Arturo (Data de defensa: 2013-03-14)
X-ray crystallography is, now at days, one of the most powerful techniques to study proteins at the atomic level. Unfortunately, obtaining high quality crystals of membrane proteins for x-ray diffraction ...
Amo Maestro, Laura del (Data de defensa: 2021-06-11)
The present thesis has established a new and state of the art mammalian protein expression system at the laboratory which has then contributed with high-yield expression for the purification and ...
González-Ortega, Emmanuel (Data de defensa: 2012-07-23)
There are several reasons to celebrate the latest advances in the treatment of the infection with HIV. According to the Joint United Nations Programme on HIV/AIDS, the number of new infections dropped ...
Villalobos Alberú, Xenia (Data de defensa: 2015-12-22)
This work is focused on the study of the stability and immunogenic properties of the Polypurine Reverse Hoogsteen hairpins (PPRHs), and on their use as a gene-silencing tool. PPRHs are non-modified DNA ...
Hospital Gasch, Adam (Data de defensa: 2014-10-13)
Macromolecular structure, and, specifically, its dynamics and flexibility, play a crucial role in its final biological function. Intense efforts are being made to obtain experimental information about ...
Rodríguez Gallego, Laura (Data de defensa: 2015-03-13)
The work presented in this thesis is focused on the study of Polypurine Reverse Hoogsteen hairpins (PPRHs) as gene silencing tools. PPRHs are double-stranded DNA molecules formed by tvvo anti parallel ...
Mingot Martí, Ares (Data de defensa: 2016-05-31)
Sweet potato feathery mottle virus (SPFMV) (Potyvirus genus, Potyviridae family) causes important yield losses in sweet potato crops, in particular in co-infections with the unrelated crinivirus Sweet ...