Universitat Politècnica de Catalunya
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The focus of this thesis is on the design, development and validation of two novel photonic sensors for the detection and characterisation of industrial and biological samples. The first one is a PSA in a collimated beam ...
The observation of biological processes in their native environments is of critical importance for life science. While substantial information can be derived from the examination of in-vitro biological samples, in-vivo ...
The study of the brain using diffuse optical methods has progressed rapidly in the recent years. The possibility of studying the cerebral microvasculature in addition to the portability and low cost of these devices, opens ...
In recent times, metallic nanoparticle plasmonics coupled with applications towards biosensing has gathered momentum to the point where commercial R&D are investing large resources in developing the so-called localized ...
Living tissues are crowded and dynamic environments, in which signalling molecules and physical forces constantly act on single cells. To ensure correct tissue development and homeostasis, cells function like small processors: ...
The main goal of this thesis was to contribute to the understanding of the nanoscale lateral organisation of key proteins in adhesion complexes. For this, we exploited single molecule localisation-based super-resolution ...
This thesis first develops new methods for high-throughput and multi-color super-resolution microscopy (Chapters 2 and 3). Subsequently, I apply these methods to study the organization of motor proteins on the lysosome ...
