Detection of particles, bacteria and viruses using consumer optoelectronic components 

    Hussain, Rubaiya (Date of defense: 2022-07-01)

    The focus of this thesis is on the design, development and validation of two novel photonic sensors for the detection and characterisation of industrial and biological samples. The first one is a PSA in a collimated beam ...

    Development of novel multimodal light-sheet fluorescence microscopes for in-vivo imaging of vertebrate organisms 

    Bernardello, Matteo (Date of defense: 2022-06-14)

    The observation of biological processes in their native environments is of critical importance for life science. While substantial information can be derived from the examination of in-vitro biological samples, in-vivo ...

    Diffuse optical monitoring of cerebral hemodynamics in experimental and clinical neurology 

    Blanco Núñez, Igor D. (Date of defense: 2015-01-31)

    The study of the brain using diffuse optical methods has progressed rapidly in the recent years. The possibility of studying the cerebral microvasculature in addition to the portability and low cost of these devices, opens ...

    Localized surface plasmon resonance for biosensing lab-on-a-chip applications 

    Acomovic, Srdjan S. (Date of defense: 2012-10-30)

    In recent times, metallic nanoparticle plasmonics coupled with applications towards biosensing has gathered momentum to the point where commercial R&D are investing large resources in developing the so-called localized ...

    Mechanisms and functions of the nucleus as a mechano-controller of cell contractility and migration plasticity 

    Venturini, Valeria (Date of defense: 2022-04-08)

    Living tissues are crowded and dynamic environments, in which signalling molecules and physical forces constantly act on single cells. To ensure correct tissue development and homeostasis, cells function like small processors: ...

    Spatiotemporal organisation of protein nanoclusters in adhesion complexes 

    Keary, Sarah (Date of defense: 2022-02-28)

    The main goal of this thesis was to contribute to the understanding of the nanoscale lateral organisation of key proteins in adhesion complexes. For this, we exploited single molecule localisation-based super-resolution ...

    Unravelling motor protein organization on lysosomal membranes with super-resolution microscopy 

    Cordier, Guillaume (Date of defense: 2018-04-03)

    This thesis first develops new methods for high-throughput and multi-color super-resolution microscopy (Chapters 2 and 3). Subsequently, I apply these methods to study the organization of motor proteins on the lysosome ...