Universitat de Barcelona
Ara mostrant els elements 403-422 de 458
Multiple studies have highlighted the role of ZEB1 as critical regulator of tumor progression through the regulation of different hallmarks of cancer beyond the induction of EMT. The general aim of this dissertation is to ...
ZEB1 is a transcription factor whose expression in cancer cells promotes tumor initiation and progression. In this study, we for the first time characterized Zeb1 and study its function in macrophages under either homeostasis ...
ZEB1 is a transcription factor best known for its role in cancer progression and metastasis. It is also expressed during embryonic development of different tissues although its function and mechanism of action have not ...
The members of ZEB family of transcription factors (ZEB1 and ZEB2) are widely known for its role in epithelial-to-mesenchymal transition (EMT), a highly relevant process during development and tumor progression. In this ...
Malaria, caused by Plasmodium falciparum parasites remains a huge public health problem and a major cause of morbidity and mortality in sub-Saharan Africa, especially among children and infants. The parasite and its vector ...
Estudis recents han demostrat una elevada freqüència de trastorns respiratoris del son (TRS) en pacients amb ictus. Presentem els tres articles que formen part de la tesi doctoral: Sleep-related breathing disorders ...
INTRODUCCIÓN: La neumonía asociada a la ventilación mecánica (NAV) es una entidad nosológica de gran importancia por su prevalencia, morbimortalidad y sobrecarga económica para el sistema sanitario y su aparición puede ser ...
The poorest outcomes in bipolar disorder are represented by self-aggressive (i.e. deliberate self-harm, attempted or completed suicide) and hetero-aggressive violent behaviors. A better understanding of the clinical factors ...
Aquest estudi intenta analitzar l'estructura del llenguatge esquizofrènic amb els mètodes desenvolupats per la lingüística estructural i l'afasiologia. S'utilitza la dicotomia sintagma/paradigma. S'hi demostra la força de ...
Los síndromes miasténicos congénitos (SMC) constituyen un grupo clínicamente heterogéneo de enfermedades de causa genética. Se caracterizan por presentar alteraciones en la transmisión neuromuscular por defectos en proteínas ...
Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin lymphomas associated with poor prognosis and frequent relapses. Recently, the neuronal transcription factor SOX11 has been identified as a very specific ...
Every year, through mass drug administration (MDA), hundreds of millions of the world’s poorest people receive a single annual dose of one or more drugs to eliminate certain parasitic worm or bacterial infections. Some of ...
The objectives of this thesis are to evaluate the strategies for expanding the donor pool by using expanded criteria donors and for increasing patient and graft survival by optimization of immunosuppression strategies. It ...
1. Generation and characterization of a radioresistant cell line In the first part of this project of Thesis, we subjected culture cells to fractionated radiation and clonal selection, to obtain a modified cohort of ...
Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by the combination of nasal polyps (NPs), chronic hypertrophic eosinophilic sinusitis, asthma and severity to any medication that inhibits ...
BACKGROUND: Surgical treatment of Insular gliomas is technically challenging and may lead to high postoperative morbidity. However, previous research has proven that maximal safe resection is critical for ...
El trabajo contenido en esta Tesis Doctoral ha ido encaminado a mejorar el conocimiento del Melanoma Familiar con el fin de mejorar su prevención y tratamiento. En el primero de los trabajos publicados se han descrito y ...
El cáncer gástrico es el resultado de sucesivos cambios histológicos en la mucosa gástrica conocidos como lesiones preneoplásicas y cuya sucesión es conocida como la Cascada de Correa, constituyendo el mecanismo de ...
The cerebral cortex is organized in complex circuits of neurons strongly interconnected in a conductive medium. During deep sleep stage, this neuronal connectivity generates recurrent synchronized synaptic activity leading ...
Malaria is a parasitic disease caused by Plasmodium parasites and it is transmitted by female Anopheles mosquito. P. falciparum has a complex life cycle that includes important stages in two different hosts: a mosquito and ...
