Universitat de Barcelona
Mostrando ítems 397-416 de 459
El 2014, el percentatge de persones de 80 anys o més va ser del 5,7 %. Segons les projeccions demogràfiques, el 2080 aquest segment de població serà del 12,3 %, això comportarà un desafiament sanitari i social. La malnutrició ...
The central scientific objective of the current dissertation was to take a multidisciplinary approach to make use of the full potential information, both scientific and clinical to aid prevention and treatment of EDs. In ...
There is an increasing awareness and visibility of transgender people, particularly in Europe and North America. Compared to the non-trans general population transgender people remain a vulnerable group with higher levels ...
The transforming growth factor-beta (TGF-β) is a cytokine involved in many physiological and pathological processes. Its dual role has been described in the liver, where it can either induce pro- or anti-apoptotic signals. ...
[eng] The arrival of antiangiogenic therapies represented a huge advance in the treatment of different tumors, such as renal carcinoma. However, despite initial good results, some tumors were able to develop different ...
Reactive oxygen species (ROS) are short-lived, highly electrophilic molecules generated by the partial reduction of oxygen to form superoxide, hydrogen peroxide and hydroxyl radical as well as other secondary metabolites. ...
“Plasmodium vivax” és el paràsit causant de malària humana amb més àmplia distribució i és responsable cada any de 100-300 milions de casos clinics, incloent algunes manifestacions severes i mort. P. vivax envaeix principalment ...
Multiple studies have highlighted the role of ZEB1 as critical regulator of tumor progression through the regulation of different hallmarks of cancer beyond the induction of EMT. The general aim of this dissertation is to ...
ZEB1 is a transcription factor whose expression in cancer cells promotes tumor initiation and progression. In this study, we for the first time characterized Zeb1 and study its function in macrophages under either homeostasis ...
ZEB1 is a transcription factor best known for its role in cancer progression and metastasis. It is also expressed during embryonic development of different tissues although its function and mechanism of action have not ...
The members of ZEB family of transcription factors (ZEB1 and ZEB2) are widely known for its role in epithelial-to-mesenchymal transition (EMT), a highly relevant process during development and tumor progression. In this ...
Malaria, caused by Plasmodium falciparum parasites remains a huge public health problem and a major cause of morbidity and mortality in sub-Saharan Africa, especially among children and infants. The parasite and its vector ...
Estudis recents han demostrat una elevada freqüència de trastorns respiratoris del son (TRS) en pacients amb ictus. Presentem els tres articles que formen part de la tesi doctoral: Sleep-related breathing disorders ...
INTRODUCCIÓN: La neumonía asociada a la ventilación mecánica (NAV) es una entidad nosológica de gran importancia por su prevalencia, morbimortalidad y sobrecarga económica para el sistema sanitario y su aparición puede ser ...
The poorest outcomes in bipolar disorder are represented by self-aggressive (i.e. deliberate self-harm, attempted or completed suicide) and hetero-aggressive violent behaviors. A better understanding of the clinical factors ...
Aquest estudi intenta analitzar l'estructura del llenguatge esquizofrènic amb els mètodes desenvolupats per la lingüística estructural i l'afasiologia. S'utilitza la dicotomia sintagma/paradigma. S'hi demostra la força de ...
Los síndromes miasténicos congénitos (SMC) constituyen un grupo clínicamente heterogéneo de enfermedades de causa genética. Se caracterizan por presentar alteraciones en la transmisión neuromuscular por defectos en proteínas ...
Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin lymphomas associated with poor prognosis and frequent relapses. Recently, the neuronal transcription factor SOX11 has been identified as a very specific ...
Every year, through mass drug administration (MDA), hundreds of millions of the world’s poorest people receive a single annual dose of one or more drugs to eliminate certain parasitic worm or bacterial infections. Some of ...
The objectives of this thesis are to evaluate the strategies for expanding the donor pool by using expanded criteria donors and for increasing patient and graft survival by optimization of immunosuppression strategies. It ...
