Now showing items 423-442 of 459
Sanz Sender, Silvia (Date of defense: 2017-04-28)
Malaria is a parasitic disease caused by Plasmodium parasites and it is transmitted by female Anopheles mosquito. P. falciparum has a complex life cycle that includes important stages in two different hosts: a mosquito and ...
Tényi, Ákos (Date of defense: 2018-07-13)
BACKGROUND: Multimorbidity (i.e. the presence of more than one chronic disease in the same patient) and comorbidity (i.e. the presence of more than one chronic disease in the presence of an index disease) are main sources ...
Prada Varela, Estela Maria (Date of defense: 2021-11-05)
Pediatric RMS is a developmental tumor that affects patients from birth to late adolescence. RMS tumorigenesis involves the stalk of embryological myogenic processes. Classically, two main subgroups of RMS have been defined ...
Giménez Carabaza, Neus (Date of defense: 2019-11-15)
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western countries. It is currently an incurable disease. CLL is a B-lymphoid neoplasm in which the microenvironment plays a key role in the development ...
Portugaliza, Harvie P. (Date of defense: 2020-12-16)
To achieve malaria elimination, great emphasis must be put on targeting the parasite’s transmissible stages, so that along with effective treatment of clinical malaria caused by asexual stages, complete interruption of the ...
Vidal Crespo, Anna (Date of defense: 2017-04-28)
In this thesis we have focused on two novel therapeutic strategies that target the crosstalk between the tumor cells and the microenvironment. Chronic lymphocytic leukemia (CLL) remains an incurable disease where high ...
Guerrero Hernández, Martina (Date of defense: 2019-02-19)
The tumor microenvironment (TME) is gaining momentum due to its contribution to cancer progression and therapy resistance. This TME has a direct crosstalk with tumor cells that involves the activation of different ...
Font Riera, Gabriel (Date of defense: 1971-01-01)
Por el nacimiento y habitual radicación en las Islas Baleares, y en tanto cursamos los estudios preuniversitarios. permitió que durante varios años llamara poderosamente nuestra atención el observar en innumerables ...
Agüera, Zaida (Date of defense: 2013-12-12)
Los Trastornos de la Conducta Alimentaria (TCA) son enfermedades mentales complejas en las que convergen numerosos de factores de riesgo y mantenimiento. La literatura previa pone de relieve la importancia de los rasgos ...
Franquesa Bartolomé, Marcela (Date of defense: 2010-01-15)
La isquèmia renal és una de les principals causes del Fracas Renal Agut i en el context del trasplantament renal predisposa l’òrgan a un dany crònic i a una possible pèrdua de l’empelt. La cèl•lula epitelial tubular ...
Canivell Fusté, Silvia (Date of defense: 2014-10-14)
The incidence of type 2 diabetes mellitus (T2D) is increasing worldwide. There are several explanations to this fact, such as the increased prevalence of obesity, population’s ageing, and the lack of physical activity ...
Ramírez Mahaluf, Juan Pablo (Date of defense: 2015-05-14)
This thesis is composed of two complementary projects. One focuses on the study of the dynamics between emotional and cognitive networks in healthy subjects using functional magnetic resonance imaging (fMRI). The second ...
Nhampossa, Tacilta Helena Francisco (Date of defense: 2013-12-20)
The objective of this thesis is to improve our understanding of the epidemiology of diarrhea, particularly to estimate the population-based burden, microbiologic etiology and adverse clinical consequences of moderate-to-severe ...
De Nigris, Valeria (Date of defense: 2015-12-03)
INTRODUCTION. It has been demonstrated that Glucagon-like peptide-1 (GPL-1) has a protective effect on endothelial cells. GLP-1 improves endothelial function in diabetes, however the mechanisms underlying the GLP-1 protective ...
Kjaergaard Bystrup, Sara (Date of defense: 2021-07-20)
[cat] El càncer colorectal (CCR) és el tercer càncer més freqüent en homes i el segon en dones a nivell mundial. Tot i que les taxes de supervivència a 5 anys en els primers estadis superen el 90%, la situació canvia ...
Gómez Aleza, Clara (Date of defense: 2021-10-25)
[spa] La vía de RANK juega un papel crucial en remodelación ósea, con un anticuerpo monoclonal (denosumab) contra el ligando de la vía de señalización (RANKL), actualmente usado en clínica contra la osteoporosis y efectos ...
Arqués Casamitjana, Oriol (Date of defense: 2015-12-04)
Colorectal cancer (CRC) is a leading cause of death worldwide, especially in the late stages of the disease when relapse and metastasis occur. Despite the improvements achieved recently in terms of treatment and diagnosis, ...
Garcia Garcia, Olga (Date of defense: 2017-04-21)
ANTECEDENTS DEL TEMA: La valoració de la coroides s’ha fet fins el 2005 amb l’angiografia amb verd d’indocianina (AVI), mètode invasiu que requereix l’ injecció d’un contrast per vena antecubital. A partir del 2010, ...
Rovira Girabal, Núria (Date of defense: 2016-06-21)
Actualment en el nostre medi només l’1-2% dels fills de mares infectades pel VIH contreuen la infecció, gràcies a les mesures preventives aplicades, fonamentades sobretot en l'ús de fàrmacs antiretrovirals. Malgrat que el ...
Duran Ferrer, Martí (Date of defense: 2020-11-19)
The DNA from our cells carries the genetic information to build a human being. This information is interpreted through epigenetic marks that lead to tightly coordinated and cell type-specific gene expression programs. One ...