Mostrando ítems 423-442 de 458
Tényi, Ákos (Fecha de defensa: 2018-07-13)
BACKGROUND: Multimorbidity (i.e. the presence of more than one chronic disease in the same patient) and comorbidity (i.e. the presence of more than one chronic disease in the presence of an index disease) are main sources ...
Prada Varela, Estela Maria (Fecha de defensa: 2021-11-05)
Pediatric RMS is a developmental tumor that affects patients from birth to late adolescence. RMS tumorigenesis involves the stalk of embryological myogenic processes. Classically, two main subgroups of RMS have been defined ...
Giménez Carabaza, Neus (Fecha de defensa: 2019-11-15)
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western countries. It is currently an incurable disease. CLL is a B-lymphoid neoplasm in which the microenvironment plays a key role in the development ...
Portugaliza, Harvie P. (Fecha de defensa: 2020-12-16)
To achieve malaria elimination, great emphasis must be put on targeting the parasite’s transmissible stages, so that along with effective treatment of clinical malaria caused by asexual stages, complete interruption of the ...
Vidal Crespo, Anna (Fecha de defensa: 2017-04-28)
In this thesis we have focused on two novel therapeutic strategies that target the crosstalk between the tumor cells and the microenvironment. Chronic lymphocytic leukemia (CLL) remains an incurable disease where high ...
Guerrero Hernández, Martina (Fecha de defensa: 2019-02-19)
The tumor microenvironment (TME) is gaining momentum due to its contribution to cancer progression and therapy resistance. This TME has a direct crosstalk with tumor cells that involves the activation of different ...
Font Riera, Gabriel (Fecha de defensa: 1971-01-01)
Por el nacimiento y habitual radicación en las Islas Baleares, y en tanto cursamos los estudios preuniversitarios. permitió que durante varios años llamara poderosamente nuestra atención el observar en innumerables ...
Agüera, Zaida (Fecha de defensa: 2013-12-12)
Los Trastornos de la Conducta Alimentaria (TCA) son enfermedades mentales complejas en las que convergen numerosos de factores de riesgo y mantenimiento. La literatura previa pone de relieve la importancia de los rasgos ...
Franquesa Bartolomé, Marcela (Fecha de defensa: 2010-01-15)
La isquèmia renal és una de les principals causes del Fracas Renal Agut i en el context del trasplantament renal predisposa l’òrgan a un dany crònic i a una possible pèrdua de l’empelt. La cèl•lula epitelial tubular ...
Canivell Fusté, Silvia (Fecha de defensa: 2014-10-14)
The incidence of type 2 diabetes mellitus (T2D) is increasing worldwide. There are several explanations to this fact, such as the increased prevalence of obesity, population’s ageing, and the lack of physical activity ...
Ramírez Mahaluf, Juan Pablo (Fecha de defensa: 2015-05-14)
This thesis is composed of two complementary projects. One focuses on the study of the dynamics between emotional and cognitive networks in healthy subjects using functional magnetic resonance imaging (fMRI). The second ...
Nhampossa, Tacilta Helena Francisco (Fecha de defensa: 2013-12-20)
The objective of this thesis is to improve our understanding of the epidemiology of diarrhea, particularly to estimate the population-based burden, microbiologic etiology and adverse clinical consequences of moderate-to-severe ...
De Nigris, Valeria (Fecha de defensa: 2015-12-03)
INTRODUCTION. It has been demonstrated that Glucagon-like peptide-1 (GPL-1) has a protective effect on endothelial cells. GLP-1 improves endothelial function in diabetes, however the mechanisms underlying the GLP-1 protective ...
Kjaergaard Bystrup, Sara (Fecha de defensa: 2021-07-20)
[cat] El càncer colorectal (CCR) és el tercer càncer més freqüent en homes i el segon en dones a nivell mundial. Tot i que les taxes de supervivència a 5 anys en els primers estadis superen el 90%, la situació canvia ...
Gómez Aleza, Clara (Fecha de defensa: 2021-10-25)
[spa] La vía de RANK juega un papel crucial en remodelación ósea, con un anticuerpo monoclonal (denosumab) contra el ligando de la vía de señalización (RANKL), actualmente usado en clínica contra la osteoporosis y efectos ...
Arqués Casamitjana, Oriol (Fecha de defensa: 2015-12-04)
Colorectal cancer (CRC) is a leading cause of death worldwide, especially in the late stages of the disease when relapse and metastasis occur. Despite the improvements achieved recently in terms of treatment and diagnosis, ...
Garcia Garcia, Olga (Fecha de defensa: 2017-04-21)
ANTECEDENTS DEL TEMA: La valoració de la coroides s’ha fet fins el 2005 amb l’angiografia amb verd d’indocianina (AVI), mètode invasiu que requereix l’ injecció d’un contrast per vena antecubital. A partir del 2010, ...
Rovira Girabal, Núria (Fecha de defensa: 2016-06-21)
Actualment en el nostre medi només l’1-2% dels fills de mares infectades pel VIH contreuen la infecció, gràcies a les mesures preventives aplicades, fonamentades sobretot en l'ús de fàrmacs antiretrovirals. Malgrat que el ...
Duran Ferrer, Martí (Fecha de defensa: 2020-11-19)
The DNA from our cells carries the genetic information to build a human being. This information is interpreted through epigenetic marks that lead to tightly coordinated and cell type-specific gene expression programs. One ...
Hernández Enríquez, Marco (Fecha de defensa: 2020-01-23)
INTRODUCTION: TAVI has settled as the standard of care of AS for inoperable, high-risk, and selected intermediate-risk patients undergoing aortic valve replacement. Vascular and bleeding complications are related to worst ...