Universitat de Barcelona
Now showing items 82-101 of 458
Insulin-like growth factor (IGF) signaling is frequently altered in HCC, including activation of IGF1R, IGF2 overexpression, IGFBP3 downregulation and IGF2R allelic losses1,2. A previous study from our group identified ...
Although chemotherapeutic drugs are widely used in order to improve the cancer outcome, drug resistance remain the most unpredictable factor affecting chemotherapy and a major impediment to successful patient’s treatment. ...
RATIONALE: Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation caused by a combination of airways disease (bronchiolitis) and parenchymal destruction (emphysema), whose relative ...
The beneficial impact of regular physical activity on cardiovascular health is well established. However, the ideal amount of exercise required to provide these benefits is not well defined, with some recent reports showing ...
Esta tesis, presentada como compendio de publicaciones, estudia diversos aspectos relacionados con el cierre percutáneo de orejuela izquierda. Está técnica, de reciente introducción, permite mantener la protección frente ...
INTRODUCTION: Community-acquired bacterial meningitis is a relevant entity related to a high morbidity and mortality, despite of the adjuvant and antibiotic treatments available. Morbidity and mortality are caused by ...
Sarcomas are a group of malignancies characterized by their bad prognosis and the absence of effective treatments. Median survival of advanced sarcoma patients is only one year in spite of treatment. Therefore, it is ...
[eng] Neuroblastoma (NB) is the most common extracranial solid childhood tumour. Its clinical and histological manifestations range from benign tumours that spontaneously regress to highly aggressive metastatic tumours ...
Malignant tumors in children and adolescents are one of the leading causes of death from disease in this population despite being rare events. The main liver tumor in children is Hepatoblastoma (HB) representing two thirds ...
Chronic schizophrenia has been widely studied, consistent findings have shown the anatomical pattern associated with this disease, but the clinical picture is often undifferentiated at first presentation. Finding morphometric ...
This work contains the efforts I have made in the last years in the field of Electrophysiological data analysis. Most of the work has been done at Starlab Barcelona S.L. and part of it at the Neurodynamics Laboratory of ...
Durante la división celular, el ADN debe estructurarse en cromosomas para asegurar un correcto reparto de la información genética a las dos células hijas. El complejo condensina, junto con el motor molecular KIF4A, son los ...
RAGE is a transmembrane protein of the immunoglobulin family highly expressed during embryonic development but rarely expressed in adult healthy tissues. However, under cellular stress RAGE is re-expressed and mediates ...
INTRODUCCIÓN Cada año mueren en el mundo más de 6 millones de niños menores de 5 años. Cerca del 50% en África subsahariana. Mejorar el conocimiento de patologías como la anemia y la exposición perinatal al VIH, que ...
This thesis is a study on the integrin-mediated mechanoresponse by binding partners and force loading rates. Regarding the binding partners, here we demonstrate an alternative and counter-intuitive mechanism, by which ...
INTRODUCCIÓN: La inflamación es un sello distintivo del cáncer. La inflamación crónica está fuertemente relacionada con el desarrollo y la progresión tumoral y suministra al tumor múltiples citoquinas proinflamatorias que ...
Esta tesis está basada en dos artículos: Articulo 1: Early first-trimester free-β-hCG and PAPP-A serum distributions in monochorionic and dichorionic twins Objetivo: Examinar la distritución en primer trimestre de ...
ANTECEDENTES: La enfermedad valvular aórtica calcificada (EVAC) es la patología valvular más prevalente en occidente, constituyendo un problema de salud pública. La presencia y cuantificación del calcio valvular tiene ...
Surgical site infections (SSI) are currently the most frequent healthcare-associated infections in Spain and Europe. Its development increases morbidity and mortality of patients and costs of healthcare system. Colorectal ...
By performing a translational study we identified a specific pattern of genes differentially regulated in patients with severe alcoholic hepatitis (AH). A functional analysis of the gene expression profile showed several ...
