Rodríguez-Vida Rodríguez, Alejo (Date of defense: 2017-10-23)
Prostate cancer is the second most frequently diagnosed cancer worldwide and the fifth leading cause of cancer death in men. Despite, the above mentioned incidence and mortality, the existence of a small ...
Roura Fornells, Esther (Date of defense: 2018-10-22)
The objective of this thesis is to estimate prospectively the association between environmental cofactors and the risk of developing cervical cancer and pre-cancer, including tobacco smoking, hormonal ...
Vegliante, Maria Carmela (Date of defense: 2013-09-26)
Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin lymphomas associated with poor prognosis and frequent relapses. Recently, the neuronal transcription factor SOX11 has been identified ...
Recalde-Percaz, Leire (Date of defense: 2021-06-30)
Metastases are considered the last stage of tumour progression and the main cause of death associated to solid tumours. There are no effective treatments for metastasis which remain non- curable with ...
Rhodes Cabrerizo, Ana Carolina (Date of defense: 2017-06-21)
ANTECEDENTES: El carcinoma hepatocelular (CHC) es el cáncer de hígado más frecuente y la sexta neoplasia con mayor incidencia mundial. Constituye la tercera causa de muerte por cáncer y la decimosexta ...
Vidal Crespo, Anna (Date of defense: 2017-04-28)
In this thesis we have focused on two novel therapeutic strategies that target the crosstalk between the tumor cells and the microenvironment. Chronic lymphocytic leukemia (CLL) remains an incurable ...
Rosich Moya, Laia (Date of defense: 2014-06-05)
La via de supervivència PI3K/AKT/mTOR es troba constitutivament activada en molts tumors, fet que ha afavorit el desenvolupament de nombrosos inhibidors al considerar-se una possible opció terapèutica. ...
Rijo Mora, Enrique Antonio (Date of defense: 2017-09-26)
INTRODUCCIÓN: MICA (Major histocompatibility complex I Chain related proteins to gen A) se expresa como respuesta al estrés celular en procesos neoplásicos, inflamatorios, infecciones virales y ...
Fernández Plana, Julen (Date of defense: 2019-01-09)
El tractament de quimioteràpia associada a fàrmacs anti-EGFR representa un estàndard de tractament oncològic per a un subgrup de pacients amb Càncer colorectal metastàtic (CCRm). Malgrat això, no tots ...
Moreno Monasterio, Marta (Date of defense: 2015-02-18)
The main goal of this PhD thesis was to understand the mechanisms underlying GBM tumor formation and progression, with a special emphasis on the study of factors that have a role in normal NSC biology, ...