Esteve Arenys, Anna (Date of defense: 2017-12-22)
Lymphomas are a heterogeneous group of tumors characterized by the proliferation of lymphocytes predominantly in lymphoid structures but also in extranodal tissues. More than 90% of patients are ...
Recasens Zorzo, Clara (Date of defense: 2018-06-19)
Constitutive activation of the chemokine receptor CXCR4 is associated with tumor progression, invasion and resistance to treatment. Overexpression of CXCR4 in diffuse large B-cell lymphoma (DLBCL) confers ...
Guerrero Hernández, Martina (Date of defense: 2019-02-19)
The tumor microenvironment (TME) is gaining momentum due to its contribution to cancer progression and therapy resistance. This TME has a direct crosstalk with tumor cells that involves the activation ...
Martínez Hernández, Daniel (Date of defense: 2016-06-27)
Los linfomas de células B son un grupo de neoplasias que tienden a imitar los estadios madurativos de la diferenciación de la célula B normal. Estos tumores pueden derivar de la expansión de un linfocito ...
García de Albéniz, Xabier (Date of defense: 2015-04-15)
We studied the mechanisms driving the metastatic spread in colorectal cancer (CRC), focusing in the MAPK pathway. We developed in vivo a highly metastatic cell line using a KRAS-mutated cell line (SW620) ...
Closa Gil, Laia (Date of defense: 2021-04-09)
La present tesi doctoral consta d’una primera part de disseny i desenvolupament d’una nova metodologia per dur a terme la seqüenciació de gens codificants de receptors de les cèl·lules NK i dels seus ...
Díaz Gay, Marcos (Date of defense: 2019-11-25)
Colorectal cancer (CRC) is one of the malignant neoplasms with higher incidence and mortality in Spain, Europe and worldwide. As a complex disease, both environmental and genetic factors influence CRC ...