Pérez Areales, Francisco Javier (Date of defense: 2017-07-14)
Alzheimer’s disease (AD) is the main neurodegenerative disorder and one of the most important health-care problems worldwide, because of its high prevalence and personal and economic impact. To aggravate ...
Amirthalingam, Ezhil (Date of defense: 2018-10-01)
This thesis has its main focus on developing multi-functional nanomaterials, that we called nano- and microtools through two different approaches, top-down to provide support and bottom up to give ...
Calderón i Almendro, Raquel (Date of defense: 2017-03-14)
Sphingolipids (SLs) are components of eukaryotic cell membranes that in the last 30 years have shown not only a structural role but also be involved in signaling processes and cellular responses. ...
Duart Castells, Leticia (Date of defense: 2020-02-25)
Drugs of abuse represent a global problem not only at a health level, but also at a social and economic extent. Recently, a tidal wave of new emerging psychoactive substances has completely modified the ...
Guignard, Guillaume Michel Pablo (Date of defense: 2016-06-23)
1. (R)-Phenylglycinol-derived oxazolopiperidone lactams can be converted to enantiopure open-chain amino ester scaffolds by alkaline hydrolysis of the N-Boc 2-piperidones resulting from the reductive ...
Montiel Achong, Juan Andrés (Date of defense: 2016-12-20)
Durante este trabajo de tesis doctoral se ha demostrado que las cloroacetamidas son intermedios de gran utilidad para la síntesis de heterociclos nitrogenados a través de procesos radicalarios o no ...
Puigoriol Illamola, Dolors (Date of defense: 2020-09-10)
The world is facing an unprecedented situation: soon the number of people over 60 years old will exceed the number of children, and more people at extreme old age than ever before. This is due to medical ...
Barniol Xicota, Marta (Date of defense: 2017-01-13)
L’objectiu de la present tesi doctoral consisteix en desenvolupar molècules policícliques de baix pes molecular que tinguin com a diana tres canals iònics específics: la viroporina A/M2 del virus de la ...
Coussanes, Gilhem (Date of defense: 2016-12-16)
The manuscript of this Doctoral Thesis has been divided into five main parts: a general introduction into the calyciphylline A-type alkaloids followed by three research chapters and conclude by a review ...
Abás Prades, Sònia (Date of defense: 2018-05-31)
The distinctive reactivity of isocyanides has been recognised as an advantageous characteristic for the formation of heterocyclic compounds. In the present manuscript new synthetic possibilities are ...