Alea Reyes, María Elisa (Date of defense: 2017-07-17)
The present thesis is included in the area of Nanomedicine and supramolecular chemistry, focused on the design and preparation of different nano and microtools for delivery, therapy and sensing. Initially, ...
Pinto, Alexandre (Date of defense: 2017-09-28)
Chiral amino alcohol derived lactams are a valuable scaffold for the enantioselective synthesis of alkaloids. In the present thesis the potential of this methodology was expanded and to demonstrate the ...
Ghashghaei, Ouldouz (Date of defense: 2017-09-26)
1. It was observed that the interaction of imines and isocyanides in the presence of a Lewis acid can lead to a variety of scaffolds including α-aminoamides, α-aminoamidines, indoles and diiminoazetidines. ...
Pérez Areales, Francisco Javier (Date of defense: 2017-07-14)
Alzheimer’s disease (AD) is the main neurodegenerative disorder and one of the most important health-care problems worldwide, because of its high prevalence and personal and economic impact. To aggravate ...
Calderón i Almendro, Raquel (Date of defense: 2017-03-14)
Sphingolipids (SLs) are components of eukaryotic cell membranes that in the last 30 years have shown not only a structural role but also be involved in signaling processes and cellular responses. ...
Barniol Xicota, Marta (Date of defense: 2017-01-13)
L’objectiu de la present tesi doctoral consisteix en desenvolupar molècules policícliques de baix pes molecular que tinguin com a diana tres canals iònics específics: la viroporina A/M2 del virus de la ...
Cosín Tomàs, Marta (Date of defense: 2017-02-28)
Epigenetic changes are currently recognized as part of the aging process and have been implicated in many age-related chronic diseases such as Alzheimer’s disease (AD). The term epigenetics includes a ...