Universitat de Barcelona
Now showing items 21-28 of 28
El perfil de seguridad de los antiinflamatorios no esteroideos (AINE) ha sido ampliamente estudiado y tanto los efectos terapéuticos como los efectos secundarios a nivel gastrointestinal (GI) y cardiovascular, se han ...
Fragment-based drug design is an established strategy of finding new drugs. Instead of doing mass screening of chemical libraries containing compounds that are already lead-like, starting from a small fragment can be be a ...
Donepezil (DPZ) is one of the most widely prescribed drugs to treat the neuropsychiatric symptoms of Alzheimer's disease (AD) which are commercially available in oral tablet form. However, these can lead to inconveniences, ...
In today’s society, people’s interest against health care is growing every day. On a health- concerned population, food supplements and nutraceuticals are products with an increasing interest among the global community. ...
El propòsit del present treball, és l’estudi de l’ús dels biopolímers alginat i chitosan per a la formulació d’hidrogels basats en xarxes polimèriques i xarxes polimèriques interpenetrants com a matrius per a la ...
Efficient discovery of bioactive molecules is an essential goal of Computer-Aided Drug Design (CADD). The molecules can be used as chemical probes, to validate novel targets, or as starting points for drug discovery. ...
Advances in structural and molecular biology have increased the knowledge of relevant and undrugged targets and have favoured the rational development of novel drugs through structure- based drug design (SBDD). ...
The research in this thesis aimed to study and generate an engineered formulation that can fuse with cell membranes and carry drugs or other compounds into cells. HeLa cells were chosen as the target cells and prior to ...
