Membrane Trafficking of TGF-β and Transcriptome Analysis in Marfan Syndrome 

Siegert, Anna-Maria Elisa (Date of defense: 2017-10-20)

Marfan Syndrome (MFS) is a rare, autosomal dominant disorder of the connective tissue that affects between 1.5 and 17.2 in 100.000 live births. MFS is caused by mutations in the extracellular matrix (ECM) glycoprotein ...