Rodríguez-García, Ana (Date of defense: 2017-09-27)
L’objectiu d’aquesta tesi doctoral és profunditzar en els mecanismes que fan de PFKFB3 un gen clau en la reprogramació metabòlica. En concret, s’estudia els mecanismes de connexió de la insulina i el ...
Greguske, Erin A. (Date of defense: 2019-07-11)
Progressive ototoxicity of the inner ear is prevalent in patients administered aminoglycoside antibiotics with little understanding of how this damage occurs and to what extent it can be recovered. ...
Hyroššová, Petra (Date of defense: 2017-05-26)
Phosphoenolpyruvate carboxykinase (PEPCK) is an enzyme that catalyses decarboxylation of oxaloacetate to phosphoenolpyruvate and it is part of gluconeogenic/glyceroneogenic pathway. There are two known ...
López Begines, Santiago (Date of defense: 2016-11-18)
In photoreceptor cells of the retina, light triggers a protein G-mediated enzymatic cascade that leads to hydrolysis of cGMP. The drop in cGMP levels causes the closure of cGMP-channel at the plasma ...
Pérez Rius, Carla (Date of defense: 2017-09-26)
El clorur compleix un conjunt de funcions essencials perquè la cèl·lula pugui realitzar correctament diferents processos fisiològics, com la regulació de l’excitabilitat en les cèl·lules musculars, ...
Simon Molas, Helga (Date of defense: 2019-07-05)
The TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) gene was described in 2006 by Dr. Karen Vousden's group in response to the induction of the tumour suppressor gene p53. Since then, numerous ...
Stanzani, Elisabetta (Date of defense: 2016-09-16)
Glioblastoma (GBM) is the most frequent and malignant primary brain tumor. The current standard of care for adult patient with diagnosed GBM is surgery followed by radiotherapy (RT) plus concomitant and ...
Aquino Martínez, Rubén Francisco (Date of defense: 2016-09-22)
At least two specific features differentiate bone from other tissues, a blend of organic and mineral components, and a cellular organization with a hierarchical commitment degree. During bone remodeling ...