Molecular insights into the promiscuity of serine hydrolases. Towards a computationally guided protocol for the redesign of enzymes 

Galmés Ordinas, Miquel Àngel (Date of defense: 2022-01-20)

Two serine hydrolases, Candida antarctica Lipase B (CALB) and para-nitrobenzyl (Bs2) esterase from Bacillus subtilis, were used as a model to study enzyme promiscuity through QM/MM methods and experimental enzymes kinetics. ...