Di Pietro, Ornella (Date of defense: 2015-11-06)
The aim of this PhD thesis consists of the synergistic combination of both highly efficient synthetic approaches and molecular modelling tools for the structure-based drug design and synthesis of novel ...
Petrov, Dmitry (Date of defense: 2015-11-20)
Global obesity is a pandemic status, estimated to affect over 2 billion people, and has resulted in an enormous strain on healthcare systems worldwide. The situation is compounded by the fact that apart ...
Valverde Murillo, Elena (Date of defense: 2015-10-30)
For over eighty years, adamantane ring has interested organic chemists for its simplicity and symmetry. The rigid tricyclo[3.3.1.13,7]decane skeleton has provided a unique structural template for ...