Integration of SHH and WNT pathways controls morphogenesis of the CNS. 

    Álvarez Medina, José Roberto (Date of defense: 2008-06-13)

    Dorsoventral patterning of the vertebrate nervous system is achieved by the combined activity of morphogenetic signals secreted from dorsal and ventral signalling centres. The Shh/Gli pathway plays a major role in patterning ...