Programa de Doctorat en Enginyeria Biomèdica: Recent submissions
Now showing items 21-40 of 108
Serum potassium concentration monitoring by ECG time warping analysis on the T wave
End-stage renal disease (ESRD) patients demonstrate an increased incidence of sudden cardiac death (SCD) with declining kidney functioning as a consequence of blood potassium ([K+]) homeostasis impairment, which is restored ...
Characterization and interpretation of cardiovascular and cardiorespiratory dynamics in cardiomyopathy patients
The main objective of this thesis was to study the variability of the cardiac, respiratory and vascular systems through electrocardiographic (ECG), respiratory flow (FLW) and blood pressure (BP) signals, in patients with ...
Optimal control prediction of assisted walking using torque-driven models : application to active orthosis simulation to assist individuals with spinal cord injury
Walking impairment after spinal cord injury leads to a decreased quality of life, other serious health conditions, and substantial health care costs. Consequently, gait restoration is a high priority among spinal cord-injured ...
Data preprocessing and quality diagnosis in deep learning-based in silico bioactivity prediction
Drug discovery is a time and resource consuming process involving the identification of a target and the exploration of suitable drug candidates for it. To streamline drug discovery, computational techniques help identifying ...
Statistical normalisation of network propagation methods for computational biology
The advent of high-throughput technologies and their decreasing cost have fostered the creation of a rich ecosystem of public database resources. In an era of affordable data acquisition, the core challenge has shifted to ...
Development of new algorithms for depth of anesthesia monitoring integrating cerebral blood flow estimations
Cerebral blood flow (CBF) reflects the rate of delivery of arterial blood to the brain. Since no nutrients, oxygen or water can be stored in the cranial cavity due to space and pressure restrictions, a continuous perfusion ...
Endurance races effects in non-elite runners by clinical biomarkers and bioimpedance measurements
Participation in marathons and ultra-endurance races is growing every day, but it is worrisome that these types of races are becoming mass events, where many runners are not sufficiently prepared. For example, in the 2017 ...
Advanced bioimpedance signal processing techniques for hemodynamic monitoring during anesthesia
Cardiac output (CO) defines the blood flow arriving from the heart to the different organs in the body and it is thus a primary determinant of global 02 transport. Cardiac output has traditionally been measured using ...
Caracterització morfològica de cèl·lules limfoides normals, reactives, anormals i blàstiques de sang perifèrica mitjançant processament digital d'imatges
The main objective of the present Doctoral Thesis is to obtain new quantitative features by means of digital image processing and machine learning for the differentiation of normal, reactive and malignant lymphoid cells ...
Enrichment of virtual screening results using induced-fit techniques
This thesis explains the design, development, test on the benchmarking dataset DUD-e and the application to an industrial virtual screening project of the PELE VS platform. The most common and quick tools used on virtual ...
Intrinsic osteoinduction and osteogenesis of biomimetic calcium phosphate scaffolds with different nano-, micro- and macroporosities : ectopic and orthotopic implantation in a canine model
The development of synthetic bone substitutes with enhanced osteogenic properties is urged by the global ageing population. Sintered calcium-phosphate (CaP) ceramics are the most widely used synthetic biomaterials for bone ...
Biointerfaces based on the combination of synthetic polymers and biomolecules
During the last decades, research focused on the preparation of highly selective and smart materials has increased considerably. For instances, it has been possible to achieve intelligent drug nano-carriers, biomolecular ...
Noves estratègies per la millora de les característiques biològiques dels implants dentals
Titanium (Ti) and its alloys are currently the materials chosen for many dental applications, mainly due to their optimum biocompatibility and excellent mechanical properties. Despite the success rates of dental implants, ...
Cell derived-extracellular matrix scaffolds with polylactic acid microcarriers for tissue engineering and cell therapy
Organ shortage for transplantation and the need for new therapies for the treatment of tissular damages have driven the development of an exciting field in research, called tissue engineering (TE). Its potential entails ...
Study of longitudinal neurodegeneration biomarkers to support the early diagnosis of Alzheimer’s disease
Alzheimer’s Disease (AD) is a progressive and neurodegenerative disorder characterized by pathological brain changes starting several years before clinical symptoms appear. Earlier and accurate identification of those brain ...
Contributions to heart rate variability and respiratory rate analysis through video imaging techniques
The present doctoral thesis proposes a series of methods that have as a general objective the non-contact evaluation of heart rate variability (HRV) and respiratory rate (BR) through video imaging. The proposal of this ...
Stimulation of wound healing and vascularization with calcium-releasing biomaterials
Chronic skin wounds are a major socioeconomic burden in developed societies, affecting specially elder and diabetic people. It is estimated that 1 to 2% of the population will suffer a chronic wound in their lifetime and, ...
Evaluación no invasiva del impulso neural respiratorio y su relación con la respuesta mecánica mediante el análisis de señales electromiográficas de músculos respiratorios
Respiratory muscle contraction occurs in response to the electrical stimulation of the muscles. These electrical stimuli originate in the respiratory neurons of the brainstem, are transmitted via motor nerves to the ...
Analysis of the Interlimb similarity of motor patterns for improving stroke assessment and neurorehabilitation
Stroke is the leading cause of adult disability, with upper limb hemiparesis being one of the most common consequences. Regaining voluntary arm movement is one of the major goals of rehabilitation. However, even with ...
Multiview pattern recognition methods for data visualization, embedding and clustering
Multiview data is defined as data for whose samples there exist several different data views, i.e. different data matrices obtained through different experiments, methods or situations. Multiview dimensionality reduction ...
