Now showing items 21654-21673 of 43211
Brugarolas Campillos, Marc (Date of defense: 2013-12-20)
The aims of this thesis are: Aim 1. The involvement of A(1)R-A(2A)R heteromer in glial cells and its study at a molecular level. Aim 2. To find evidence for allosteric interactions between partner receptors in the ...
Margalef González, Pol (Date of defense: 2014-02-17)
L’IKKα nuclear regula la transcripció gènica i ha estat relacionada amb la progressió del càncer i la metàstasis, tot i que la connexió mecanística no s’entén massa bé. Hem observat que les ...
Zhang, Yu (Date of defense: 2018-11-28)
El fruit del préssec deriva de l'ovari madur, que es converteix en drupa. La seva forma pot variar entre rodona i plana, adquirint algunes formes intermèdies com la forma aplanada. En el préssec, el fruit pla (anomenat ...
Mayayo Vallverdú, Clara (Date of defense: 2021-11-29)
[eng] Cystinuria, with a worldwide prevalence estimated at 1:7000, is a rare inherited disease characterized by urine hyperexcretion of cystine and dibasic amino acids. Its clinical manifestation is cystine lithiasis in ...
Rivera Brugués, Núria (Date of defense: 2012-03-20)
Genomic microarray analysis is rapidly replacing conventional chromosome analysis by molecular karyotyping due to the significant increase in the power to detect causative CNVs. Here, we extensively validated the HumanHap550 ...
Núñez Hernández, Fernando (Date of defense: 2016-09-30)
Cuatro estudios diferentes fueron llevados a cabo con el fin de analizar la expresión de microRNAs (miRNAs) porcinos y virales en dos infecciones in vivo diferentes con circovirus porcino tipo 2 (PCV2) y el virus de la ...
Delgado Serrano, Luisa Fernanda (Date of defense: 2021-12-02)
Human cancer arises as a result of genomic alterations that transform cells and make them to grow without control and to pathological levels. The characterization of such genomic changes has enabled understanding tumor ...
González Rosado, Santiago (Date of defense: 2016-04-28)
The genetic and molecular bases of most of the human diseases have become one of the main goals of the human biology in the last decades. To be able to unveil the genetic variations and the affected cellular processes ...
García Vidal, Edurne (Date of defense: 2019-10-15)
La terapia antirretroviral ha cambiado la perspectiva sobre la infección por VIH-1 de enfermedad letal a crónica. Aun así, el reservorio latente del VIH-1 es una de las mayores barreras para lograr una cura. La estrategia ...
Alcaine Colet, Anna (Date of defense: 2019-11-04)
The self-renewing nature of embryonic stem cells (ESCs) is a consequence of their ability to proliferate while maintaining pluripotency, by means the capacity to differentiate into all adult cell types. Despite the remarkable ...
Doñate Macian, Pablo (Date of defense: 2016-07-13)
Los canales TRPV son canales de cationes que participan en la homeostasis del calcio con propiedades de activación polimodales. Los TRPVs regulan los niveles de calcio intracelular y promueven ...
Atienza García, María Terersa (Date of defense: 2018-02-13)
The work underlying this Thesis, has contributed to the main study and characterization of diffusive systems. The research work has been focused on the analysis of two kind of systems. On the one hand, the dynamics of ...
Sequeiros Fontán, Tamara (Date of defense: 2014-11-27)
El cáncer de próstata (CP) es una de las mayores causas de muerte entre los hombres de los países desarrollados. Sin embargo, los actuales métodos de diagnóstico presentan una elevada tasa de falsos positivos debido a su ...
Žonja, Božo (Date of defense: 2017-02-01)
Pharmaceuticals which are used worldwide are designed to facilitate the life for the human society and have an important role in treatment and prevention of disease for both humans and animals. They are ubiquitous in the ...
Barriga de Vicente, Francisco Martín (Date of defense: 2013-11-28)
The first chapter of this thesis describes the study of intestinal stem cells (ISCs) and their relationship to colon cancer. We describe the transcriptional landscape of intestinal epithelial populations through the use ...
Henryka Gawrzak, Sylwia (Date of defense: 2016-11-23)
Breast cancer is the most frequently diagnosed cancer and remains the second leading cause of death among women in Europe and United States. In this malignancy, metastasis remains to be an incurable condition, and therefore ...
Rotstein Bajo, Bárbara (Date of defense: 2013-03-22)
A stereotyped tubular epithelial network forms many of our bodies’ organs and, defects in the formation of these tubules often leads to organ failure. My Thesis project aims to further understand the mechanisms underling ...
Roca Ayats, Neus (Date of defense: 2019-11-18)
Osteoporosis is a complex disease, determined by genetic and environmental factors, characterized by a low bone mass and microarchitectural deterioration of bone tissue, with a consequent decrease of bone strength and ...
Mingot Martí, Ares (Date of defense: 2016-05-31)
Sweet potato feathery mottle virus (SPFMV) (Potyvirus genus, Potyviridae family) causes important yield losses in sweet potato crops, in particular in co-infections with the unrelated crinivirus Sweet potato chlorotic stunt ...
Manrique Ramírez, Paula Constanza (Date of defense: 2013-11-18)
Haemophilus parasuis es una bacteria Gram negativa común en el tracto respiratorio superior de cerdos sanos y es el agente etiológico de la enfermedad de Glässer, que se caracteriza por poliserositis fibrinosa y poliartritis. ...