Universitat de Barcelona
Now showing items 10913-10932 of 11223
Patients with hereditary breast and ovarian cancer (HBOC) in whom a causative pathogenic variant is not identified after genetic analysis may not benefit from prevention, early detection, or precision treatment measures. ...
[eng] Seabirds and fisheries share the same fishing resources and grounds, resulting in their inevitable interaction, with significant conservation implications for the firsts. Seabirds scavenging on fishery waste modify ...
[eng] 80% of breast cancer (BC) express positive estrogen receptors (ER+) and up to 15% of them also overexpress or amplify the human epidermal growth factor receptor 2 (HER2), which confers a molecular biology and different ...
Long noncoding RNAs (lncRNAs) have proven biological roles in plethora cellular contexts. Nonetheless, only a handful have been clearly characterized, leaving thousands of newly discovered lncRNAs without an associated ...
In photoreceptor cells of the retina, light triggers a protein G-mediated enzymatic cascade that leads to hydrolysis of cGMP. The drop in cGMP levels causes the closure of cGMP-channel at the plasma membrane, decreasing ...
B lymphopoiesis is the result of several cell lineage choices and differentiation steps whose perturbation leads to B cell malignancies. Cellular transitions for B cell generation have been associated with gene activation ...
Enzymes have attracted the attention of chemists and biologists since long ago due to their molecular complexity and tremendous efficiency. They are highly specific catalysts that make chemical reactions possible at mild ...
In plants, the sterol biosynthetic pathway leads to the production of a complex mixture of end-products, among which β-sitosterol, stigmasterol, campesterol, and cholesterol are the most abundant ones. Stigmasterol, the ...
Chloroplasts provide plants with metabolic pathways that are unique among eu- karoytes, including the methylerythritol 4-phosphate pathway (MEP) for the pro- duction of isoprenoids essential for photosynthesis and plant ...
[eng] Lysinuric Protein Intolerance (LPI) is a rare autosomal recessive disorder caused by mutations in the SLC7A7 gene, which encodes the y+LAT1 transporter. LPI presents a pleiotropic phenotype that varies among patients, ...
[eng] Endometrial cancer represents the most common cancer arising from the uterine cavity and there is little hope for patients with recurrent or metastatic disease. Prior studies of our group reported autophagy pathway ...
Influenza A virus is one of the most outstanding human viruses. The major treatments against influenza are small analogues, monoclonal antibodies and vaccines, however, due to the fast mutation of the seasonal influenza ...
My general objective with this thesis is to contribute to the search for connections between postcolonial and critical understandings in urban studies. Building on my analysis of the urban trajectories of Rio de Janeiro’s ...
Chapter 2 of this dissertation estimates the joint causal effect of highway and railway Infrastructure on the suburbanization of population in European cities. Using a unique dataset of 579 European cities from 29 European ...
Aquesta tesi és un estudi exhaustiu sobre la ciutat de Girona a partir de l'anàlisi dels diferents burgs o barris que la configuren. Aquestes unitats urbanístiques seran estudiades a partir de diferents vessants. En ...
El present estudi posa en comú la recerca prèvia i fa noves propostes sobre l’urbanisme i l’arquitectura de la ciutat romana de Pollentia. A pesar de que eren diversos els edificis descoberts al llarg de les excavacions, ...
[spa] Esta tesis se teje desde un iniciático proceso para comprender las construcciones subjetivas de profesoras de Artes Visuales a raíz de una nueva política curricular, entendida esta como dispositivo, y junto con ello ...
La génesis de los tumores de urotelio es aun hoy un capitulo desconcertante. Existe la polémica de si el carcinogeno induce su acción sobre el epitelio a través de la orina o bien incide por vía hemática a través del ...
La finalidad de esta investigación es elaborar un conjunto de directrices sobre experiencia de usuario (UX) que guíen el diseño de las webs de periódicos para smartphones. Para ello, el trabajo se articula en dos bloques ...
Protein-protein interactions are essential in biological processes and thus, they have become very promising therapeutic targets. Nevertheless, the artificial modulation of protein complexes remains a challenge. Since most ...
