Universitat de Barcelona
Ara mostrant els elements 5303-5322 de 11082
En una primera parte de la Tesis se ha conseguido establecer la validez de los radicales 1-carbamoildiclorometilo para reaccionar con cualquier tipo de alquenos (empobrecidos, enriquecidos y no activados). De esta forma ...
[eng] The field of Artificial Intelligence (AI) has undergone a revolution in recent years with the advent of more efficient computing hardware and well-documented software for model development. Many fields are being ...
Over the past few decades, machine learning (ML) algorithms have become a very useful tool in tasks where designing and programming explicit, rule-based algorithms are infeasible. Some examples of applications ...
Esta Tesis Doctoral ha consistido en el estudio de los mecanismos implicados en la comorbilidad entre el abuso de drogas y los trastornos de ansiedad, así como en las regiones cerebrales responsables de la coexistencia de ...
La presente tesis está formada por 4 publicaciones científicas que tienen por objetivo analizar e identificar genes y vías moleculares implicadas en la predisposición y desarrollo del cáncer cutáneo. Por un lado, se ha ...
The present dissertation, which can be framed in the fields of behavioural and psychiatric genetics, was aimed to study how early environmental factors such as parental negativity and childhood adversity, directly or in ...
Il pensiero teoretico del filosofo italiano Michele Federico Sciacca è il tema principale di questa tesi di dottorato. Sciacca si interessò costantemente alla cultura spagnola e amò la Spagna quanto una seconda patria, ...
The finding of a suite of unusual minerals associated to ophiolitic chromitites questions traditional model for the formation of these rocks. These findings include minerals typically considered indicators of ultra-high ...
Numerous initiatives to improve our understanding of cancer biology have been lunched in different laboratories that aim to describe the interactome and gene-expression profile in different tumour cell line. It is now ...
The main aim of this work was to characterize the molecular mechanisms that underlie the physiopathology of LCA12 and RP10, that are inherited retinal dystrophies caused by alterations in guanine nucleotide metabolism. First, ...
There is an incomplete understanding of the heritability and the specific genetic bases of Obsessive-Compulsive Disorder (OCD). It has a complex multifactorial etiology comprising both biological as well as psychosocial ...
Colorectal cancer (CRC) is a major health burden with large numbers of new cases worldwide and high disease-specific mortality, despite great advances made towards improving patient clinical outcomes. It arises through the ...
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental, complex and highly heritable disorder characterised by age-inappropriate symptoms of inattention, impulsivity and hyperactivity that impair the daily ...
Sanfilippo C syndrome is a lysosomal storage disorder that presents an autosomal recessive inheritance pattern and is caused by mutations in the HGSNAT gene, identified in 2006 in the chromosome 8. This gene codes for a ...
[eng] Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Research in the past decade has led to major progress in understanding the genetic etiology of the disease; since I started my PhD (2019), nearly ...
The overarching aim of the present thesis project is to implement new testing strategies and develop new tools that will contribute to improve the genetic diagnosis of hereditary cancer, with the ultimate goal of individualizing ...
Cerebrovascular disease is the leading cause of disability in adults. Independent of clinical variables such as infarct size and location, stroke subtype, and vascular risk factors, individuals have disparate responses ...
Cancer was reported as the second leading cause of death in 2018 by the World Health Organisation. Cancer is defined as the set of diseases that proceeds in multiple phases generating a transformation lead by an accumulation ...
Low risk Human Papillomaviruses (LR-HPVs) 6 and 11 are the main causative agents of benign proliferative lesions such genital warts (GWs) and recurrent respiratory papillomatosis (RRP) (Aubin et al. 2008; Ball et al. 2011; ...
[eng] Substance use disorders (SUDs) are psychiatric disorders characterized by a recurring desire to continue taking a substance regardless of its destructive consequences. The etiology of SUDs is complex and multifactorial, ...
