Mostrando ítems 101-110 de 205
Rodríguez Escribà, Marta (Fecha de defensa: 2020-01-21)
Transfer RNAs (tRNAs) are key adaptor molecules that mediate decoding of messenger RNAs (mRNAs) into proteins by complementary pairing of their anticodons with mRNA codons. tRNAs that undergo adenosine ...
Malandrino, Maria Ida (Fecha de defensa: 2013-10-04)
Current lifestyle with high-energy diets and little exercise is triggering an alarming growth in obesity. Excess of adiposity is leading to severe increase in associated pathologies, such as insulin ...
Zamora Ramírez, William J. (Fecha de defensa: 2019-02-22)
Lipophilicity is a key physicochemical descriptor used to understand the biological profile of (bio)organic compounds, xenobiotics and a broad variety of biochemical, pharmacological, and toxicological ...
Sostoa Pomés, Jana de (Fecha de defensa: 2019-05-31)
Oncolytic virus (OV)-based therapies have an emerging role in the treatment of solid tumors, involving both direct cell lysis and immunogenic cell death. Nonetheless, tumor- associated stroma limits the ...
Fajardo Calderón, Carlos Alberto (Fecha de defensa: 2017-05-19)
Oncolytic adenoviruses that selectively replicate in cancer cells while sparing normal tissue have gained considerable attention as novel anticancer drugs. However, clinical trials with these viruses ...
Jiménez Panizo, Alba (Fecha de defensa: 2021-12-14)
El receptor de glucocorticoides (GR) es un factor de transcripción que se expresa de forma ubicua y controla procesos esenciales para la vida como el metabolismo, la inflamación y la homeostasis. Aunque ...
Gratacòs Batlle, Esther (Fecha de defensa: 2010-12-16)
Carnitine palmitoyltransferase 1 (CPT1) catalyzes the conversion of long chain fatty acyl-CoAs into acylcarnitines, the first step in the transport of long chain fatty acids from the cytoplasm to the ...
Ventura Ventanachs, Verònica (Fecha de defensa: 2013-10-18)
Irosustat is a first-generation, irreversible, steroid sulfatase inhibitor currently in development for hormone-dependent cancer therapy. Its structure is a tricyclic coumarin-based sulfamate that ...
Pantazi, Eirini (Fecha de defensa: 2015-07-06)
Ischemia-reperfusion injury (IRI) is an inevitable situation in clinical settings such as liver transplantation and hepatic resection. It develops when blood flow is interrupted for a long period of ...
Robles García, Virginia (Fecha de defensa: 2014-12-05)
Clathrin is an evolutionary conserved molecule that coats membranes endocytosed from the plasma membrane and those that move between the trans-Golgi network (TGN) and endosomes of eukaryotic cells. It ...