Mostrando ítems 21-30 de 173
Llorente Lope, Alicia (Fecha de defensa: 2021-03-23)
Metastatic breast cancer (BCa) is the leading cause of death in BCa patients. Current therapies for BCa aim at cell proliferation and, therefore, latent disseminated cells are able to escape treatment. ...
Pérez Salvia, Montserrat (Fecha de defensa: 2019-03-01)
Cancer is considered nowadays a genetic and epigenetic disease. Aberrancies in epigenetic marks in DNA and histone tails together with alterations in epigenetic regulators responsible of catalyzing ...
Matas Gironella, Júlia (Fecha de defensa: 2021-12-20)
Colorectal cancer (CRC) is a major health burden with large numbers of new cases worldwide and high disease-specific mortality, despite great advances made towards improving patient clinical outcomes. ...
Celià Terrassa, Antoni (Fecha de defensa: 2012-05-14)
This Doctoral Thesis project is part of a broader research program whose global aim is to better understand key molecular and cellular events in tumor metastasis, in particular those associated with ...
Benítez, Sandra (Fecha de defensa: 2021-01-13)
Receptor activator of nuclear factor kappa-β ligand (RANKL) and its receptor RANK are key mediators of bone resorption1,2. RANKL, its receptor RANK and its natural decoy receptor OPG, which is a competitive ...
Noguera-Castells, Aleix (Fecha de defensa: 2022-01-31)
Modern oncology conceives solid tumours as organs by themselves, meaning that not only should the behaviour of cancer cells to be considered and evaluated therapeutically, but also the so-called tumour ...
Casal Domínguez, María (Fecha de defensa: 2018-02-16)
Inflammatory myopathy (IM) is a heterogeneous group of diseases characterized by muscle weakness and inflammatory infiltrates on the muscle biopsy. But muscle involvement is not always present and other ...
López Solà, Clara (Fecha de defensa: 2015-07-24)
There is an incomplete understanding of the heritability and the specific genetic bases of Obsessive-Compulsive Disorder (OCD). It has a complex multifactorial etiology comprising both biological as ...
Royo Garrido, Romina (Fecha de defensa: 2023-03-31)
[eng] Next-generation sequencing (NGS) has revolutionized biomedical sciences, especially in the area of cancer. It has nourished genomic research with extensive collections of sequenced genomes that ...
Manzano Muñoz, Albert (Fecha de defensa: 2022-12-15)
[eng] Personalized medicine has emerged to improve cancer treatment beyond classical approaches. The identification of genetic mutations by molecular analyses dominate personalized medicine initiatives ...