Font Díaz, Joan (Date of defense: 2022-07-22)
Nuclear receptors are a superfamily of ligand-dependent transcription factors that are involved in numerous biological processes in homeostasis and disease. Liver X receptors (LXRs) are members of the ...
Montal Roura, Robert (Date of defense: 2020-10-07)
[spa] El cáncer hepatobiliar (incluye principalmente el carcinoma hepatocelular [HCC] y el cáncer del tracto biliar [BTC]) representa la tercera causa de muerte relacionada con cáncer en todo el mundo ...
Serra Camprubí, Queralt (Date of defense: 2023-07-27)
[eng] The field of cancer treatment has shifted towards personalized medicine, driven by advancements in understanding molecular and genetic abnormalities and identifying specific targets within cancer ...
Boix Sánchez, Olga (Date of defense: 2022-10-11)
[eng] Recent advances in computational analyses, peptidomics and ribosome profiling have revealed that many regions previously annotated as non-coding are in fact translated into a myriad of bioactive ...
Perramón Corominas, Meritxell (Date of defense: 2022-10-17)
[eng] Chronic liver diseases are one of the most prevalent diseases worldwide. The study of the signaling pathways involved in the fibrogenic process as well as the evaluation of novel therapies such ...
Rué Cabré, Laura (Date of defense: 2012-07-12)
La malaltia de Huntington és un trastorn neurodegeneratiu progressiu causat per una expansió de repeticions del triplet CAG (més de 37) en l’exó 1 del gen de la huntingtina que genera una proteïna ...
Castillo Écija, Helena (Date of defense: 2022-03-22)
Therapy development in cancer involves several consecutive steps including (1) the identification of the unmet medical need (disease or clinical question), (2) the establishment of clinically relevant ...
Súarez López, Lucía (Date of defense: 2013-07-05)
Durante la división celular, el ADN debe estructurarse en cromosomas para asegurar un correcto reparto de la información genética a las dos células hijas. El complejo condensina, junto con el motor ...
Garin Escrivà, Noé (Date of defense: 2015-04-17)
INTRODUCTION Although the need for comprehensive management of patients with multiple co-occurring conditions has been highlighted, policies and guidelines are still focused on the management ...
Martínez Redondo, Paloma (Date of defense: 2014-06-25)
The chromatin consists of a hierarchical and dynamical structure that is modulated during the different cell cycle stages in order to maintain genome integrity and preserve the genetic information coded ...