Repchevskiy, Dmitry (Date of defense: 2016-02-05)
The aim of this thesis is to develop standard and practical approaches for the semantic integration of biological data and services. The thesis considers various scenarios where ontologies may benefit ...
Massó Barnadas, J. Oriol (Date of defense: 1994-01-01)
La presente tesis es un estudio detallado de la respuesta antígena in vivo a través de la respuesta humoral sérica y celular esplénica y ganglionar; al estudio de la dinámica de las distintas poblaciones ...
Carulla i Sanmartí, Pere (Date of defense: 2017-12-01)
Un dels principals aspectes que hem descrit ha estat la presència i la distribució de les isoformes de pI de l’LPL. Inicialment hem treballat amb teixits de rata adulta: cor, TAB, TAM i múscul. Els ...
Sfriso, Pedro (Date of defense: 2016-03-18)
Sequence, structure and dynamics are an indivisible tandem to understand protein function. Luckily, evolution imposed a hierarchical rational between that facilitates the analysis: dynamics are encoded ...
López Ferrando, Víctor (Date of defense: 2019-12-11)
Single amino acid variants (SAVs) are one of the main causes of Mendelian disorders, and play an important role in the development of many complex diseases. At the same time, they are the most common ...
Cairó Calzada, Montserrat (Date of defense: 2017-07-19)
El teixit adipós marró (TAM) està format principalment per adipòcits marrons, la funció principal dels quals és el manteniment de la temperatura corporal de l’organisme a través de la termogènesi ...
Ivani, Iván (Date of defense: 2016-12-13)
Classical force fields are the core of classical simulations, particularly of molecular dynamics (MD), a technique that is changing our view on the structure, flexibility and function of biological ...
Azagra Rodríguez, Alba (Date of defense: 2019-11-29)
B lymphopoiesis is the result of several cell lineage choices and differentiation steps whose perturbation leads to B cell malignancies. Cellular transitions for B cell generation have been associated ...
Castellano Escuder, Pol (Date of defense: 2021-09-08)
This thesis is the product of three and a half years working on the complex world of metabolomics and nutrition. All the work presented here is focussed on the problems arising from associating ...
Cajal Visa, Yolanda (Date of defense: 1993-01-01)
En esta tesis doctoral se ha pretendido profundizar en los mecanismos de interacción péptido-lípido, puesto que los mismos determinan gran parte de las propiedades estructurales y funcionales de las ...