Martín López, Juan (Date of defense: 2022-07-15)
The present Thesis is divided in three chapters: 1. Design and synthesis of new soluble epoxide hydrolase inhibitors (sEHI) The synthesis of new soluble epoxide hydrolase inhibitors based on ureas ...
Bergamino Sirvén, Milana Arantza (Date of defense: 2022-11-29)
[eng] 80% of breast cancer (BC) express positive estrogen receptors (ER+) and up to 15% of them also overexpress or amplify the human epidermal growth factor receptor 2 (HER2), which confers a molecular ...
Cortés Serra, Núria (Date of defense: 2022-11-24)
[eng] American tripanosomiasis or Chagas Disease (CD), caused by the parasite Trypanosoma cruzi (T. cruzi), remains one of most neglected tropical diseases. Endemic from 21 countries in Latin America, ...
Pérez Guillén, Isabel (Date of defense: 2022-11-25)
[eng] Bacteria have been to the human civilization a threat as well as an ally, since the beginning of time. The introduction of antibiotics into clinics to treat infections was one of the best medical ...
Bardini, Giulia (Date of defense: 2022-11-30)
[eng] INTRODUCTION: In the last twenty years, sealing cements based on tricalcium silicate cements have been introduced into the market for orthograde filling of the root canal system. These silicate-based ...
Pérez Jaume, Sara (Date of defense: 2022-12-15)
[eng] INTRODUCTION: A diagnostic test is a measurement taken from a subject with the aim of diagnosing a certain condition of interest, such as diseased patient or healthy individual. Typically, ...
Garcia Mulero, Sandra (Date of defense: 2022-12-16)
[eng] Cancer is a heterogeneous disease, in which many cell types interact with cancer cells, forming a complex network. The crosstalk between the cancer cells and the immune microenvironment is determinant ...
Motos Galera, Ana (Date of defense: 2022-12-21)
[eng] INTRODUCTION: Nosocomial pneumonia caused by Pseudomonas aeruginosa is associated with high mortality and morbidity. Furthermore, the high incidence of multi-resistance to antimicrobials makes ...
Nogué i Garrigolas, Laura (Date of defense: 2023-11-28)
[eng] Introduction Congenital heart defects are the most common severe congenital malformations. Since prenatal diagnosis is optimal, current research focuses on studying cardiovascular remodeling to ...
Morante Palacios, Octavio (Date of defense: 2022-06-02)
[eng] Monocytes are highly plastic cells and possess the ability to differentiate into cell types with very different immunological properties. Depending on the external stimuli and the specific immune ...