Mostrando ítems 1-10 de 18
Lorente Crivillé, Adriana (Fecha de defensa: 2014-07-18)
Natural products from terrestrial plants and microorganisms have long been a traditional source of drugs. For centuries humans have been looking on their environment for medicines to treat illnesses. ...
Mendive Tapia, Lorena (Fecha de defensa: 2017-02-17)
In the present thesis we have investigated the development of new methodologies for the selective and straightforward chemical modification of Trp amino acid either alone or in peptides. In the first ...
Rocas Alonso, Pau (Fecha de defensa: 2016-02-25)
This thesis, entitled "Multifunctional Self-stratified Polyurethane-Polyurea Nanosystems for Smart Drug Delivery" is structured as a compendium of publications, being organized around a methodological ...
Paradís Bas, Marta (Fecha de defensa: 2015-05-15)
The known as "difficult peptides", as well as those sequences that aggregate in solution, are some of those molecules with high applicability as nanomaterials or even in medicine field. This thesis has ...
Just Baringo, Xavier (Fecha de defensa: 2013-11-25)
The present doctoral thesis has been devoted to the development of a new synthetic strategy to obtain a new member of the thiopeptide, or thiazolyl peptide, family of antibiotics. This new member, ...
Isidro Llobet, Albert (Fecha de defensa: 2008-05-13)
The increasing importance of peptides as drugs creates the necessity of new methodologies for the synthesis of complex peptides. This PhD thesis has been focused on the development of new protecting ...
Palà Pujadas, Judith (Fecha de defensa: 2018-03-12)
Chemical protein synthesis has become a potent tool for the synthesis of proteins, especially those which are not easily accessed by DNA recombinant methods, such as proteins with posttranslational ...
Fransen, Peter (Fecha de defensa: 2013-12-05)
Dendrimers are a class of globular highly branched macromolecules with precise architecture. They consist of a multivalent surface with functional group, a core unit where branching starts, and the ...
Fernández-Llamazares Onrubia, Ana Iris (Fecha de defensa: 2013-12-09)
Backbone N-methylation is becoming an increasingly important tool in peptide drug design, and has been widely used to optimize the activity and selectivity of peptide ligands as a result of conformational ...
Miret Casals, Laia (Fecha de defensa: 2014-05-23)
CHAPTER 1: Respiratory Infectious Diseases (RID) are diseases affecting the air passages, the bronchi and the lungs. They range from acute infections, such as pneumonia and bronchitis, to chronic ...