Now showing items 1-20 of 11205

    Machine Learning for predicting Immunotherapy response from routine Medical Imaging 

    Ligero Hernández, Marta (Date of defense: 2024-03-15)

    [eng] HYPOTHESIS: Precision oncology has revolutionized the landscape of cancer treatment. Emerging therapeu- tic approaches, such as immunotherapy or anti-angiogenic agents, have exhibited remarkable outcomes in solid ...

    Enhancing CAR-T Cell Therapy for Hematological Malignancies through Dual Targeting and Combination with NK Cells 

    Bachiller García, Mireia (Date of defense: 2024-03-06)

    [eng] CAR-T therapy has represented a milestone for the treatment of hematological patients in relapse or refractory to conventional treatments, leading to the approval by regulatory agencies of four CAR-T products against ...

    Fetal programming in assisted reproductive technologies 

    Boutet, Maria Laura (Date of defense: 2022-10-26)

    [eng] INTRODUCTION: Pregnancies conceived through assisted reproductive techniques (ART) represent up to 7.9% of births in European countries, with an increasing trend. The safety aspects of ART have gained relevance in ...

    Predictive Modelling for Personalised Multimorbidity Management 

    González Colom, Rubèn (Date of defense: 2024-01-29)

    [eng] Multimorbidity affects equally individuals and healthcare systems. Multimorbidity is associated with poor prognosis, functional impairment, and reduced quality of life, leading to increased healthcare resource ...

    Investigating malaria transmission and assessing control activities in preparation for a malaria elimination strategy in the Lihir Islands of Papua New Guinea 

    Millat Martínez, Pere (Date of defense: 2024-01-31)

    [eng] INTRODUCTION: Papua New Guinea (PNG) has the highest malaria transmission rates in the Pacific region. The Lihir Islands of PNG comprise the islands of Aniolam, where a gold mine is located, Masahet, Mahur and ...

    Assessing Value in Lung Cancer Treatment: A Detailed Cost-Benefit Analysis of Clinical Management Strategies 

    Guzmán Portillo, Rudith (Date of defense: 2024-02-23)

    [eng] INTRODUCTION: Lung cancer represents a serious health problem because, although it is one of the most common types of cancer, it is also the one with the highest mortality. This high mortality is due to the asymptomatic ...

    Deciphering pathomechanisms underlying genetic lipid disorders of the brain 

    Planas Serra, Laura (Date of defense: 2024-03-15)

    [eng] Over the last decade, a common driver of genetic brain disorders that has emerged is the alteration of lipid metabolism. In this thesis, we sought to gain an understanding of the pathomechanisms underlying genetic ...

    Spatial Ecology of the Endangered Egyptian Vulture: from Distribution and Movement to Biological Conservation 

    Cerecedo Iglesias, Catuxa (Date of defense: 2024-06-14)

    [eng] The current rampant loss of biodiversity is known to be affecting human well-being the world over. Sustainability has become the global go-to solution to ensure the balance between economic growth, social well-being ...

    Impact of Stress on Pregnancy Mental Health 

    Pascal Capdevila, Rosalia (Date of defense: 2024-03-15)

    [eng] INTRODUCTION: Disturbances in perinatal mental health and sleep quality are problems Usual. In addition, stress can induce dysbiosis of the maternal microbiota. The available scientific evidence highlights the ...

    Lacosamida y fenitoína como tratamientos del dolor en la neuralgia del trigémino 

    Muñoz Vendrell, Albert (Date of defense: 2024-03-15)

    [spa] La presente tesis se enfoca en evaluar dos hipótesis principales: 1. Los fármacos endovenosos que actúan como bloqueadores de los canales de sodio fenitoína y lacosamida son tratamientos eficaces y seguros para ...

    Essays on Violence, Health and Family Dynamics 

    Beigelman, Marie (Date of defense: 2024-06-11)

    [eng] Violence is a pervasive societal challenge with profound economic implications. The experience of violence can have durable impacts on the life-outcomes of victims: their health; labor market opportunities, educational ...

    Individualización de la presión de perfusión media en cirugía cardíaca para la prevención de la lesión renal aguda y sus consecuencias en pacientes de riesgo 

    Molina Andújar, Alícia (Date of defense: 2024-03-15)

    [spa] La lesión renal aguda (LRA) es un síndrome clínico caracterizado por la pérdida de la función renal debida a una disminución brusca del filtrado glomerular (FG) en un corto plazo de tiempo (horas, días). Puede ser ...

    ARNs no codificantes como biomarcadores predictivos y pronósticos de la quimio-radioterapia neoadyuvante en cáncer de recto 

    Benítez Montañez, José Carlos (Date of defense: 2024-03-14)

    [spa] INTRODUCCIÓN: El cáncer colorrectal es uno de los tumores más frecuentes en ambos sexos. En este contexto, es de especial interés el estudio del cáncer de recto, cuyo tratamiento principal cuando no es metastásico ...

    Desarrollo de herramientas y estrategias para la optimización de la viroterapia oncolítica con adenovirus 

    Otero Mateo, Marc (Date of defense: 2024-03-14)

    [spa] El adenocarcinoma ductal de páncreas (PDAC) es una neoplasia muy agresiva con una incidencia prácticamente igual a la mortalidad y con una tasa de supervivencia a los 5 años de alrededor del 10%. Se estima que para ...

    Assessment of bone loss adjacent to lower second molar in case of third molar impaction and other findings using Orthopantomography (OPG) 

    Assiri, Hassan (Date of defense: 2024-03-13)

    [eng] INTRODUCTION: Dental impaction is a pathological situation in which a tooth is totally or partially included in the jaw or maxilla bone. Different teeth are noticeably prone to impaction phenomena, including the ...

    Clinical markers shaping the trajectory of bipolar disorder 

    Fico, Giovanna (Date of defense: 2024-03-13)

    [eng] INTRODUCTION: Bipolar disorder (BD) is a severe psychiatric disorder characterized by recurring mood episodes of depression or (hypo)mania with a prevalence in the general population of 2%. The clinical course and ...

    EUDONORGAN a blended-learning programme to improve organ donation knowledge in the European Union and Neighbouring countries: Prospective study 

    Peralta Lasso, Patricia (Date of defense: 2024-03-12)

    [eng] Developing training actions in organ donation and transplantation is key to improving viability, efficiency and donation rates. The European Union and neighbouring countries have promoted educational initiatives, ...

    Utilidad del Video Head Impulse Test en Población Infantil: Valores Normales y sus Alteraciones en la Patología más Frecuente 

    Rodríguez Villalba, María Rosana (Date of defense: 2024-03-06)

    [spa] El vértigo y el mareo son síntomas que se presentan frecuentemente en la infancia y la adolescencia. En los últimos años, ha crecido el interés por la evaluación de la función vestibular en niños, principalmente ...

    Study of the role of cell-matrix force transmission in naive to primed pluripotency transition in mouse embryonic stem cells 

    Viswandha Venkata Naga Sai, Srivatsava (Date of defense: 2024-03-07)

    [eng] “Doing the right thing, at the right time, to the right extent, in the right manner, and for the right purpose”. This isn’t a shoddy attempt at virtue signalling by invoking Aristotle. It rather is my philosophical ...

    Preferencias temporales en orangutanes y bonobos 

    Salas Morellón, Laura (Date of defense: 2016-12-02)

    [spa] Constantemente, los seres humanos y otros animales eligen cómo comportarse, y sus decisiones tienen consecuencias que se desarrollan con el tiempo. El estudio de las preferencias temporales explora cuánto valora un ...