TDX (Tesis Doctorals en Xarxa)

Universitat de Barcelona: Recent submissions

Now showing items 21-40 of 12206

Mètodes de diagnòstic complementaris al diagnòstic histopatològic 

López Prades, Sandra (Date of defense: 2025-07-09)

[cat] INTRODUCCIÓ: La EspAax és una malaltia inflamatòria crònica que afecta principalment la columna vertebral i les articulacions sacroilíaques. Els pacients poden desenvolupar un dany estructural significatiu, la qual ...

Utilidad de la cromoendoscopia virtual y dispositivo de inteligencia artificial para la detección endoscópica de lesiones colorrectales 

Ortiz Zúñiga, Oswaldo (Date of defense: 2025-07-09)

[spa] La tesis doctoral de Oswaldo Ortiz Zúñiga, titulada "Utilidad de la cromoendoscopia virtual y dispositivo de inteligencia artificial para la detección endoscópica de lesiones colorrectales", se centra en la evaluación ...

Illuminating cAMP signalling in neurodegenerative diseases: from synaptic plasticity mechanisms to therapeutic opportunities 

Sitjà Roqueta, Laia (Date of defense: 2025-07-08)

[eng] With the ageing of the population, neurodegenerative diseases represent a growing public health problem, which could lead to an unsustainable social and economic burden if current trends persist. Surprisingly, most ...

Non-Traditional Strategies To Fight Antimicrobial Resistance in Gram-Negative Bacteria: From Cyclic Peptides To Antibacterial Plasmids 

Rosón Calero, Natalia (Date of defense: 2025-07-07)

[eng] With the aging population, the rising burden of neurodegenerative diseases presents a critical public health issue, potentially resulting in an unsustainable social and economic burden if current trends continue. ...

Caracterización Clínica, Molecular y Pronóstica de la Leucemia Mielomonocítica Crónica 

Castaño Díez, Sandra (Date of defense: 2025-07-04)

[spa] INTRODUCCIÓN: La leucemia mielomonocítica crónica (LMMC) es una neoplasia hematológica que combina características de los síndromes mielodisplásicos y de las neoplasias mieloproliferativas. Se caracteriza por monocitosis ...

Eficàcia de noves pautes de tractament antibiòtic de l’endocarditis enterocòcica avaluades in vitro i al model d’endocarditis experimental 

García González, Javier (Date of defense: 2025-07-04)

[cat] INTRODUCCIÓ: L’endocarditis enterocòcica ha incrementat de manera progressiva la seva incidència als darrers quaranta anys fins a convertir-se a la tercera causa d’endocarditis. Entorn a un 90% dels episodis són ...

CircRNA and piRNAs as Biomarkers in Non-Small Cell Lung Cancer: Their Role in Tumor Progression and Patient Outcome 

He, Yangyi (Date of defense: 2025-07-04)

[eng] Introduction: Non-small cell lung cancer (NSCLC) is the most common lung cancer, accounting for 85% of cases. It is divided into pulmonary adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC), which differ in ...

Cancer epidemiology in the kidney failure population 

Oliveras Pagès, Laia (Date of defense: 2025-07-03)

[eng] Introduction: People with kidney failure have a higher risk of cancer compared to age- and sex-matched individuals in the general population, especially after kidney transplantation. Moreover, mortality after a cancer ...

Minimally Invasive Chevron-Akin osteotomy for Correction of Moderate and Severe Hallux Valgus Deformities: An Anatomical, Clinical and Radiological Study 

Alencar Mendes de Carvalho, Kepler (Date of defense: 2025-07-02)

[eng] INTRODUCTION: Minimally invasive surgical (MIS) treatment of hallux valgus (HV) deformities has experienced exponential growth in the last decade. Many studies on this technique have been published, including clinical ...

Avances en el Trastorno Obsesivo-Compulsivo infantil y adolescente: el papel de Terapia Cognitivo-Conductual concentrada y la acomodación familiar 

Hermida Barros, Laura (Date of defense: 2025-07-01)

[spa] INTRODUCCIÓN: El Trastorno Obsesivo-Compulsivo afecta aproximadamente al 1% de la población infantil y adolescente y, si no se trata adecuadamente, puede seguir un curso crónico, impactando significativamente en la ...

Individualització de la profilaxi de la malaltia tromboembòlica venosa en pacients pediàtrics afectes de leucèmia limfoblàstica aguda: ús del test de generació de trombina 

Ruiz Llobet, Anna (Date of defense: 2025-07-01)

[cat] INTRODUCCIÓ El tromboembolisme venós (TEV) és una complicació freqüent en pacients pediàtrics amb leucèmia limfoblàstica aguda (LLA), amb una incidència de fins al 50%, associada a una major morbiditat i mortalitat. ...

Cribado de hipofosfatasia en individuos con niveles de fosfatasa alcalina disminuida mediante la definición de percentiles de fosfatasa alcalina en una selección de centros sanitarios nacionales 

Castells Vilella, Laura (Date of defense: 2025-06-30)

[spa] INTRODUCCIÓN: La hipofosfatasia (HPP) es una enfermedad rara hereditaria progresiva y sistémica del metabolismo calcio-fósforo, caracterizada por un déficit de actividad de la fosfatasa alcalina (FA) debida a ...

Combinatorial Gene Editing in Human Cells to Model Deficiencies of DNA Repair in Cancer 

McCullough Figueras, Marcel (Date of defense: 2025-06-30)

[eng] DNA repair mechanisms are essential for maintaining genome stability, yet the intricate interactions between various repair pathways remain incompletely understood. Despite the growing recognition of genetic interactions ...

SARS-CoV-2 en la población pediátrica: Transmisión y dinámica de anticuerpos 

Pons Tomàs, Gemma (Date of defense: 2025-06-26)

[spa] La infección por SARS-CoV-2 ha representado un reto global con importantes repercusiones sanitarias y socioeconómicas. Comprender la transmisión y la respuesta inmunitaria ha sido clave para la vigilancia epidemiológica ...

Novel molecular mechanisms involved in neuronal migration during cortical development 

Peregrina Cabredo, Claudia (Date of defense: 2025-06-20)

[eng] The cerebral cortex is an evolutionarily advanced brain structure that processes sensory, motor and cognitive information. Its complex organization reflects the differentiation patterns and cell migration that take ...

SARS-CoV-2 vaccination at a High-Complexity Reference Hospital: Implementation and results of an active pharmacovigilance program 

Sáez Peñataro, Joaquín (Date of defense: 2025-06-20)

[eng] INTRODUCTION: The severe acute respiratory syndrome coronavirus-2 virus (SARS-CoV-2) is the causative agent of the COVID-19 pandemic, which has infected hundreds of millions of people and caused millions of deaths ...

Impacto de la dimensión social de la sostenibilidad en la elección de alimentos: Una exploración de las preocupaciones societales de los jóvenes a través de métodos implícitos y explícitos 

Bermúdez Ruiz, Alejandra Ximena (Date of defense: 2025-07-24)

[spa] La toma de decisiones alimentarias se ha estudiado principalmente mediante medidas explícitas (autoinformadas) y a nivel individual, asumiendo que la evaluación y elección entre alternativas se realiza de forma ...

Macrophage iron metabolism dysregulation in psoriasis 

Brischetto, Agnese (Date of defense: 2025-06-19)

[eng] Macrophages are the most plastic immune cells, representing the first line of defence after the physical barriers and acting as antigen-presenting cells to activate the adaptive immunity. They are present in the ...

Development of an in vitro LTP-model of food anaphylaxis and study of mechanisms driving exacerbated responses 

Ollé Boix, Laia (Date of defense: 2025-06-19)

[eng] Mast cells (MCs), key immune system cells, can be activated via IgE or the MRGPRX2 receptor, releasing proinflammatory mediators that may trigger severe allergic reactions such as anaphylaxis. The study aims to better ...

Transient sources with LST-1: study of novae, supernovae, and gamma-ray bursts 

Aguasca i Cabot, Arnau (Date of defense: 2025-09-23)

[eng] The branch of astrophysics that studies transient phenomena allows the exploration of astronomical sources that show temporal variability that can extend from a few fractions of a second to scales as long as tens of ...