Universitat de Barcelona
Now showing items 31-40 of 54
During the past years working in Ernest Giralt’s group, I’ve been involved in three different subprojects that constitute one of the three chapter of my thesis and have the same common link: the use of ...
The work of this thesis is based on research on peptides able to cross the blood-brain barrier and their use as tools to enable the delivery of drugs into the brain. The blood-brain barrier (BBB) is ...
Prolyl oligopeptidase (POP) is an 81-KDa bidomain enzyme which hydrolyses short proline-containing peptides. This enzyme is involved in mnemonic and cognitive processes, and the dysregulation of POP ...
In the course of this thesis, the optimal epitopes for the subsequent polyclonal rabbit antibody production for cTnI and NT-proBNP have been studied and chosen. cTnI and NT-proBNP are the most relevant ...
A fast and direct surface plasmon resonance (SPR) method for the kinetic analysis of the interactions between peptide antigens and immobilised monoclonal antibodies (mAb) has been established. Protocols ...
Molecular electronics is an emergent area of the new technologies related to the use of organic and biological materials in optoelectronic and electronic devices. Among the materials used in electronic ...
1. Introduction TomB/YmoB family of proteins was proposed as antitoxins of Hha/YmoA family of proteins. Toxin antitoxin (TA) systems are involved in the regulation of biofilm in bacteria, among other ...
Nowadays, the discovery and development of novel constrained peptides which are likely to combine the advantages of therapeutic proteins with those of small molecules is of special interest. This has ...
This doctoral thesis was focused on the design and synthesis of novel chiral ligands for application in asymmetric catalysis. One of the best examples of asymmetric catalysis is the asymmetric hydrogenation ...
This work is divided in 2 different parts: Part A: Cyclization and conjugation can confer on biomolecules better activity, resistance toward enzymatic degradation and better internalization ...
