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Cyclin D3 and CDK11 partnership in pancreatic beta cell homeostasis in autoimmune diabetes. Studies on the NOD mouse model

Sengupta, Upasana (Date of defense: 20-01-2014)
Cyclin D3 and CDK11 are downregulated in pancreatic islet endocrine cells during the autoimmune attack progression in autoimmune-prone NOD (Non-obese diabetic) mouse strain. D-type cyclins are crucial in order to connect ...
The role of cyclin D3 in pancreatic β-cell metabolic fitness and viability in a cell cycle-independent manner. Implications in autoimmune diabetes

Saavedra Ávila, Noemí Alejandra (Date of defense: 26-09-2013)
La diabetis tipus 1 (DM1) és una malaltia autoimmune causada per la destrucció de cèl·lules productores d'insulina β en els illots pancreàtics, aquesta destrucció és mediada per limfòcits. En aquesta tesi es pretén donar ...